Evidence map›Paper›PMID 36260273›Full record

ArticleHormones (Athens, Greece)2023

Association of erectile dysfunction with diabetic foot and its outcomes in type 2 diabetic men.

Adriana Coppola, Pietro Gallotti, Tiziana Montalcini, Ileana Terruzzi, Arturo Pujia, Livio Luzi, Carmine Gazzaruso

Abstract read
PubMed Publisher
In one paragraph

Article in Hormones (Athens, Greece), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adriana CoppolaDiabetes and Endocrine-Metabolic Diseases Unit, Istituto Clinico Beato Matteo, Gruppo Ospedaliero San Donato, Corso Pavia 84, 27029, Vigevano, Italy.
Pietro GallottiDiabetes and Endocrine-Metabolic Diseases Unit, Istituto Clinico Beato Matteo, Gruppo Ospedaliero San Donato, Corso Pavia 84, 27029, Vigevano, Italy.
Tiziana MontalciniDepartment of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy.
Ileana TerruzziDepartment of Endocrinology, IRCCS Multimedica, Milan, Italy.
Arturo PujiaDepartment of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy.
Livio LuziDepartment of Endocrinology, IRCCS Multimedica, Milan, Italy.
Carmine GazzarusoDiabetes and Endocrine-Metabolic Diseases Unit, Istituto Clinico Beato Matteo, Gruppo Ospedaliero San Donato, Corso Pavia 84, 27029, Vigevano, Italy. c.gazzaruso@gmail.com.ORCID http://orcid.org/0000-0001-9974-0735
University of Milan · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeErectile dysfunction (ED) and diabetic foot (DF) are common complications in patients with diabetes. However, the relationship between ED and DF has been little studied. In particular, no study has evaluated whether ED is associated with the outcomes of DF. The aim of this retrospective cohort study was to investigate whether ED is a predictor of the outcomes of DF in a large population of men with DF.

methodsThree hundred and twenty-six consecutive men with type 2 diabetes and a recent and single DF ulcer were recruited and followed up for 41.7 ± 22.7 months.

resultsAmong men with DF, 56.1% had ED (ED group) and 43.9% did not (NO ED group). Wound healing rate was significantly higher in the NO ED than in the ED group (90.2 versus 73.3%; p = 0.0001). Minor amputation rate (13.7 versus 4.8%; p = 0.007) and mortality (25.7 versus 0.7%; p < 0.001) were significantly greater in the ED than in the NO ED group. Among 263 patients with healed ulcers, recurrence rate was significantly higher in the ED than in the NO ED group (51.5 versus 26.3%; p < 0.001). Multivariate analysis showed that the absence of ED was associated with wound healing (OR: 0.459; 95% CI: 0.213-0.993; p = 0.048), while the presence of ED predicted mortality (OR: 22.644; 95% CI: 2.976-34.271; p = 0.002) and DF recurrence (OR: 3.498; 95% CI: 1.882-6.499; p < 0.001).

conclusionsOur data show that among men with DF the prevalence of ED is very high. Moreover, ED may be a strong predictor of wound healing, mortality, and ulcer recurrence.

Indexed as

Diabetes Mellitus, Type 2Diabetic FootErectile DysfunctionHumansMaleRetrospective StudiesUlcerDiabetic footErectile dysfunctionMortalityPrognosisType 2 diabetesWound healing

Identifiers

PMID36260273
OpenAlexW4306796158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.