Evidence map›Paper›PMID 36260213›Full record

ArticleAging clinical and experimental research2022

Glomerular filtration rate by different measures and albuminuria are associated with risk of frailty: the Rugao Longitudinal Ageing Study.

Hui Zhang, Meng Hao, Yi Li, Xiaoyan Jiang, Mengjing Wang, Jing Chen, Xiaofeng Wang, Xuehui Sun

Abstract read
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In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hui ZhangHuman Phenome Institute and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Meng HaoHuman Phenome Institute and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Yi LiHuman Phenome Institute and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xiaoyan JiangKey Laboratory of Arrhythmias, Ministry of Education, Department of Pathology and Pathophysiology, School of Medicine, Tongji University, Shanghai, China.
Mengjing WangNational Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jing ChenNational Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xiaofeng WangHuman Phenome Institute and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xuehui SunHuman Phenome Institute and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China. xhsun@fudan.edu.cn.
Fudan University · CNHuashan Hospital · CNTongji University · CN

Funding

Shanghai Municipal Science and Technology Major Project 2017SHZDZX01the National Key R&D Program of China 2018YFC2000400the National Key R&D Program of China 2018YFC2000400-3the National Key R&D Program of China 2018YFC2002000
6 · The paper itself

Abstract

BACKGROUND AND

aimA decreased estimated glomerular filtration rate (eGFR) is associated with frailty, but the association between kidney function and frailty using multidimensional assessments has not been entirely examined. We aimed to investigate whether albuminuria and the eGFR using different biomarkers were associated with frailty.

methodsA total of 1830 older adults were included. Kidney function was assessed by the eGFR (based on combined creatinine-cystatin C [eGFR

resultsAt baseline, kidney function was associated with prevalent frailty. During the 2-year follow-up, a decreased eGFR (per 10 units) was associated with an increased risk of incident frailty using the FP (eGFR

conclusionKidney function decline and CKD were associated with an increased risk of prevalent and incident frailty in older adults. Physicians should pay more attention to monitoring frailty status in older adults with CKD, even in those with kidney function decline.

Indexed as

FrailtyRenal Insufficiency, ChronicAlbuminuriaBiomarkersCreatinineCross-Sectional StudiesGlomerular Filtration RateHumansRisk FactorsBiomarkersCreatinineAlbuminuriaeGFRFrailtyKidney function decline

Identifiers

PMID36260213
OpenAlexW4306784144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.