Evidence map›Paper›PMID 36260188›Full record

ArticleVeterinary research communications2023

Knema retusa is antibacterial and antibiofilm against antibiotic resistant Staphylococcus aureus and S. haemolyticus isolated in bovine mastitis.

Julalak Chuprom, Kamchai Kidsin, Suthinee Sangkanu, Veeranoot Nissapatorn, Christophe Wiart, Maria de Lourdes Pereira, Tuempong Wongtawan, Mareena Daus, Dennapa Saeloh Sotthibandhu, Varomyalin Tipmanee and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Veterinary research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Whole Genome Sequence Analysis of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Veterinary world · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Julalak ChupromAkkhraratchakumari Veterinary College, Walailak University, 80160, Nakhon Si Thammarat, Thailand.
Kamchai KidsinAnimal Health Section, Department of Livestock Development, The Eight Reginal Livestock Office, 84000, Surat Thani, Thailand.
Suthinee SangkanuSchool of Allied Health Sciences, Southeast Asia Water Team (SEA Water Team), World Union for Herbal Drug Discovery (WUHeDD), and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, 80160, Nakhon Si Thammarat, Thailand.
Veeranoot NissapatornSchool of Allied Health Sciences, Southeast Asia Water Team (SEA Water Team), World Union for Herbal Drug Discovery (WUHeDD), and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, 80160, Nakhon Si Thammarat, Thailand.
Christophe WiartThe Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah, Jalan UMS, Kota Kin-abalu, 88400, Sabah, Malaysia.
Maria de Lourdes PereiraDepartment of Medical Sciences, CICECO-Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal.
Tuempong WongtawanAkkhraratchakumari Veterinary College, Walailak University, 80160, Nakhon Si Thammarat, Thailand.
Mareena DausDivision of Physical Science and Natural Product Center of Excellent, Faculty of Science, Prince of Songkla University, 80160, Songkhla, Thailand.
Dennapa Saeloh SotthibandhuFaculty of Medical Technology, Prince of Songkla University, 90110, Songkhla, Thailand.
Varomyalin TipmaneeDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, 90110, Songkhla, Thailand.
Alok K PaulSchool of Pharmacy and Pharmacology, University of Tasmania, 7001, Hobart, TAS, Australia.
Charles Norman ScholfieldAkkhraratchakumari Veterinary College, Walailak University, 80160, Nakhon Si Thammarat, Thailand.
Masyitah Binti ZulkipliSchool of Pharmacy, University of Nottingham Malaysia Campus, 43500, Semenyih, Malaysia.
Nor Hayati AbdullahNatural Product Division, Forest Research Institute Malaysia (FRIM), 52109, Kepong, Malaysia.
Watcharapong MitsuwanAkkhraratchakumari Veterinary College, Walailak University, 80160, Nakhon Si Thammarat, Thailand. watcharapong.mi@wu.ac.th.ORCID http://orcid.org/0000-0002-5257-4626
Walailak University · THPrince of Songkla University · THForest Research Institute Malaysia · MYUniversiti of Malaysia Sabah · MYUniversity of Aveiro · PTUniversity of Nottingham Malaysia Campus · MYUniversity of Tasmania · AU

Funding

Center of Excellence in Innovation of Essential Oil, Walailak University WU-COE-65-05Thailand Science Research and Innovation Fund FRB650082/0227Walailak University WU-IRG-64-023
6 · The paper itself

Abstract

This study aimed to assess antibacterial activity of Knema retusa wood extract (KRe) against antibiotic resistant staphylococci which are causative agents of bovine mastitis. From 75 cases of intramammary infections in dairy cows, 66 staphylococcal isolates were collected, including 11 Staphylococcus aureus isolates (17%) and 55 coagulase-negative staphylococci (83%). Sixty isolates (91%) formed strong biofilms. KRe had minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) against the isolates ranging 32-256 ug/mL and 64-512 ug/mL, respectively. Two-hour KRe exposures at 4×MIC, viabilities of S. aureus and S. haemolyticus decreased by 3 log

Indexed as

Cattle DiseasesMastitis, BovineMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsBiofilmsCattleFemaleMicrobial Sensitivity TestsMolecular Docking SimulationStaphylococcusStaphylococcus aureusAnti-Bacterial AgentsBiofilmsBovine mastitisKnema retusa extractStaphylococciViability

Identifiers

PMID36260188
OpenAlexW4306756174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.