Evidence map›Paper›PMID 36259786›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2023

COVID-19 increased in Italian children in the autumn and winter 2021-2022 period when Omicron was the dominant variant.

Antonietta Curatola, Serena Ferretti, Benedetta Graglia, Lavinia Capossela, Giulia Menchinelli, Barbara Fiori, Antonio Chiaretti, Maurizio Sanguinetti, Antonio Gatto

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonietta CuratolaDepartment of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-2430-9876
Serena FerrettiDepartment of Pediatrics, Catholic University of the Sacred Heart, Rome, Italy.ORCID 0000-0001-6479-1540
Benedetta GragliaDepartment of Pediatrics, Catholic University of the Sacred Heart, Rome, Italy.
Lavinia CaposselaDepartment of Pediatrics, Catholic University of the Sacred Heart, Rome, Italy.
Giulia MenchinelliDepartment of Basic Biotechnological Sciences, Intensivology and Perioperative Clinics, Catholic University of the Sacred Heart, Rome, Italy.
Barbara FioriDepartment of Laboratory and Infectious Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Antonio ChiarettiDepartment of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Maurizio SanguinettiDepartment of Basic Biotechnological Sciences, Intensivology and Perioperative Clinics, Catholic University of the Sacred Heart, Rome, Italy.
Antonio GattoDepartment of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-8778-9328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe examined the prevalence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children during the autumn and winter season from 1 September 2021 to 30 January 2022 and compared it with the same period in 2020-2021.

methodsThis study was carried out int the paediatric emergency department (PED) of a tertiary Italian hospital. We compared the clinical and demographical features of all children who presented during the two study periods and tested positive for SARS-CoV-2.

resultsDuring the 2021-2022 autumn and winter season 5813 children presented to the PED, 19.0% were tested for SARS-CoV-2 and 133 (12.0%) of those tested positive. In 2020-2021, 2914 presented to the PED, 12.3% were tested, and 30 (8.3%) of those tested positive. There were no statistically significant differences in clinical severity during the two study periods, despite a higher percentage of neurological symptoms in 2020-2021. Of the SARS-CoV-2-positive cases, 29/133 (21.8%) were hospitalised during the 2021-2022 season and 10/30 (33.3%) during the previous one. Only 3/163 children required intensive care.

conclusionThe greater spread of SARS-CoV-2 was probably due to the greater transmissibility of the Omicron variant, but the symptoms were mild and only 3 children required intensive care.

Indexed as

COVID-19ChildCritical CareHumansSARS-CoV-2Seasonsclinical severityOmicron variantpaediatric emergency departmentpandemic

Identifiers

PMID36259786
PMCPMC9874380

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.