Evidence map›Paper›PMID 36259485›Full record

ArticleRenal failure2022

Clinical characteristics and outcomes of antibiotic-associated encephalopathy in patients with end-stage kidney disease.

Qingxiu Huang, Jianbo Li, Naya Huang, Xi Xia, Yagui Qiu, Zhong Zhong, Zhenchuan Lin, Xiaowen Huang, Dihua Zhang, Fengxian Huang

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Qingxiu HuangDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jianbo LiDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Naya HuangDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xi XiaDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yagui QiuDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhong ZhongDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhenchuan LinDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaowen HuangZhongshan Hospital of Traditional Chinese Medicine, Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.
Dihua ZhangDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Fengxian HuangDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNGuangzhou University of Chinese Medicine · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEnd-stage kidney disease (ESKD) patients have a higher risk of antibiotic-associated encephalopathy (AAE) than other patients. We aimed to evaluate the prevalence, risk factors and outcomes of AAE in ESKD patients.

methodA retrospective study of ESKD patients treated with intravenous antibiotics in our hospital from Jan. 1, 2006, to Dec. 31, 2015 was performed. AAE was diagnosed by the modified Delphi method. Control individuals were randomly selected from the remaining patients who did not exhibit neurologic symptoms. Logistic regression analysis was used to identify risk factors for AAE as well as the association between AAE and outcome.

resultA total of 2104 patients were included in the study. The prevalence of AAE in our study was 4.4% (92/2104). The multivariate logistic regression analysis revealed that anuria (OR = 8.04, 95% CI: 4.13-15.65,

conclusionThe prevalence of AAE was 4.4% in ESKD patients and varied among different antibiotics. Anuria, history of central nervous system disorder and hypoalbuminemia were associated with AAE in ESKD patients. AAE is associated with worse outcomes in ESKD patients.

Indexed as

AnuriaBrain DiseasesHypoalbuminemiaKidney Failure, ChronicAnti-Bacterial AgentsHumansRegistriesRetrospective StudiesAnti-Bacterial AgentsAntibiotic-associated encephalopathyend-stage kidney diseaseoutcomesprevalencerisk factors

Identifiers

PMID36259485
PMCPMC9586608
OpenAlexW4306779882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.