Evidence map›Paper›PMID 36259480›Full record

ArticleCell journal2022

Granulosa Cell Conditioned Medium Enhances The Rate of Mouse Oocyte In Vitro Maturation and Embryo Formation.

Zeinab Bahrami, Narges Hatamian, Mahmood Talkhabi, Elnaz Zand, David G Mottershead, Rouhollah Fathi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zeinab BahramiDepartment Of Animal Sciences , Faculty Of life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Narges HatamianDepartment Of Animal Sciences , Faculty Of life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Mahmood TalkhabiDepartment Of Animal Sciences , Faculty Of life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Elnaz ZandDepartment of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
David G MottersheadSchool of pharmacy and Bioengineering , Keele University, ST58G, UK.
Rouhollah FathiDepartment of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Royan Institute · IRKeele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMATERIALS AND

methodsIn the experimental study, fresh/non-vitrified and vitrified-warmed mouse germinal vesicle (GV) oocytes (as F and V) were

resultsThese analyses showed that GCCM significantly increased the IVM rate, oocyte meiotic resumption and mitochondrial membrane potential (P<0.05). In addition, the rate of IVF and two-cell embryo formation was significantly higher in FGM and VGM compared to FBM and VBM (P<0.05). Interestingly, GCCM significantly affected the expression of the studied genes.

conclusionOur findings suggest that GCCM might be useful for improving the efficiency of IVM and the subsequent IVF outcomes.

Indexed as

Conditioned mediumIn vitro fertilizationIn vitro maturationVitrification

Identifiers

PMID36259480
PMCPMC9617018
OpenAlexW4306830509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.