ArticleRenal failure2022
Earlier continuous renal replacement therapy is associated with reduced mortality in rhabdomyolysis patients.
Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Observational studies of early versus late salvage therapies in critical care exhibit intrinsic selection bias: two meta-analyses.Critical care (London, England) · 2025Pooled it
- Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysis-associated acute kidney injury.EMBO molecular medicine · 2026Article
- Association between the use of β-adrenergic receptor blockers and all-cause mortality in sepsis-associated rhabdomyolysis syndrome: a cohort study.Frontiers in medicine · 2026Article
- Article
- Extracorporeal pediatric renal replacement therapy: diversifying application beyond kidney failure.Pediatric nephrology (Berlin, Germany) · 2025Review
- Efficacy of haemoadsorption combined with continuous renal replacement therapy in patients with rhabdomyolysis and acute kidney injury: a retrospective study.Clinical kidney journal · 2025Article
- Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb.Nature communications · 2025Article
- Predicting 28-Day Mortality in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Novel Interpretable Machine Learning Approach.Journal of multidisciplinary healthcare · 2025Article
- Perioperative Rhabdomyolysis in Obese Individuals Undergoing Bariatric Surgery: Current Status.Healthcare (Basel, Switzerland) · 2024Review
- Rare skin color changes in an acute pancreatitis patient undergoing maintenance hemodialysis.BMC nephrology · 2024Article
- Rhabdomyolysis as cause, consequence, or mimicker of myocardial infarction: A case report.Clinical case reports · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContinuous renal replacement therapy (CRRT) is commonly employed for rhabdomyolysis (RM) patients. However, the optimal initiation timing of CRRT and prognostic factors were not well evaluated for patients with RM. We aimed to investigate the efficacy of CRRT timing on mortality and the risk factors for death in RM patients who received CRRT.
methodsRM patients who received CRRT between 1 May 2010 and 31 May 2021 in our center were retrospectively included. Univariate and multivariate logistic analyses were performed to identify the risk factors for primary outcome (90-day mortality).
resultsA total of 134 patients were included in our study. The 90-day mortality rate was 38.06%. The median time from CRRT initiation to peak CK occurrence was 4.8 h (IQR -16, 14), 67 patients received CRRT before 4.8 h after peak CK occurrence (early CRRT), and 67 patients received CRRT beyond 4.8 h after peak CK occurrence (late CRRT). Multivariate logistic regression analysis showed that the time from CRRT initiation to the peak CK (per 1 h, OR 1.026, 95% CI 1.004-1.049,
conclusionsEarlier CRRT initiation before 4.8 h after peak CK occurrence was associated with lower 90-day patient mortality.
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