Evidence map›Paper›PMID 36259463›Full record

ArticleeLife2022

A spatiotemporal reconstruction of the

Muntasir Kamal, Levon Tokmakjian, Jessica Knox, Peter Mastrangelo, Jingxiu Ji, Hao Cai, Jakub W Wojciechowski, Michael P Hughes, Kristóf Takács, Xiaoquan Chu and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Pre-cuticle DPY-6 acts as a blueprint for aECM periodic organization inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Persistent effects of early-life arsenic exposure inEnvironmental science. Processes & impacts · 2026
    Article
  5. Article
  6. Article
  7. MLT-11 is necessary forbioRxiv : the preprint server for biology · 2025
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 6 countries.

Muntasir Kamal *Department of Molecular Genetics, University of Toronto, Toronto, Canada.
Levon Tokmakjian *The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada.
Jessica Knox *Department of Molecular Genetics, University of Toronto, Toronto, Canada.ORCID 0000-0003-1465-5852
Peter MastrangeloDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Jingxiu JiDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.ORCID 0000-0003-4121-7719
Hao CaiMolecular Medicine Program, The Hospital for Sick Children, Toronto, Canada.
Jakub W WojciechowskiWroclaw University of Science and Technology, Faculty of Fundamental Problems of Technology, Department of Biomedical Engineering, Wroclaw, Poland.ORCID 0000-0001-5289-653X
Michael P HughesDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, United States.
Kristóf TakácsPIT Bioinformatics Group, Institute of Mathematics, Eötvös University, Budapest, Hungary.
Xiaoquan ChuCenter for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Jianfeng PeiDepartment of Computer Science and Technology, Tsinghua University, Beijing, China.
Vince GrolmuszPIT Bioinformatics Group, Institute of Mathematics, Eötvös University, Budapest, Hungary.ORCID 0000-0001-9456-8876
Malgorzata KotulskaWroclaw University of Science and Technology, Faculty of Fundamental Problems of Technology, Department of Biomedical Engineering, Wroclaw, Poland.ORCID 0000-0002-2015-5339
Julie Deborah Forman-KayMolecular Medicine Program, The Hospital for Sick Children, Toronto, Canada.ORCID 0000-0001-8265-972X
Peter J RoyDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.ORCID 0000-0003-2959-2276
University of Toronto · CAInstitute of Mathematics and Informatics · BGWrocław University of Science and Technology · PLHospital for Sick Children · CAPeking University · CNSt. Jude Children's Research Hospital · USTsinghua University · CN

Funding

Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
CIHR 313296CIHR 376634NIH HHS R24 OD010943
6 · The paper itself

Abstract

How the cuticles of the roughly 4.5 million species of ecdysozoan animals are constructed is not well understood. Here, we systematically mine gene expression datasets to uncover the spatiotemporal blueprint for how the chitin-based pharyngeal cuticle of the nematode

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsChitinLarvaMoltingProteinsCaenorhabditis elegans ProteinsChitinProteinsC. eleganscuticledevelopmental biologyintrinsically disordered proteinsmoltingnovel gene familiesphase separationsystems analyses

Identifiers

PMID36259463
PMCPMC9629831
OpenAlexW4306784391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.