Evidence map›Paper›PMID 36259456›Full record

Observational studyJournal of neurotrauma2023

Association Between Serum Neurofilament Light and Glial Fibrillary Acidic Protein Levels and Head Impact Burden in Women's Collegiate Water Polo.

Megan E Huibregtse, Sage H Sweeney, Mikayla R Stephens, Hu Cheng, Zhongxue Chen, Hannah J Block, Sharlene D Newman, Keisuke Kawata

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of neurotrauma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Megan E HuibregtseDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, Georgia, USA.
Sage H SweeneyDepartment of Kinesiology and College of Arts and Sciences, Indiana University, Bloomington, Indiana, USA.
Mikayla R StephensDepartment of Kinesiology and College of Arts and Sciences, Indiana University, Bloomington, Indiana, USA.
Hu ChengDepartment of Department of Psychological and Brain Sciences and College of Arts and Sciences, Indiana University, Bloomington, Indiana, USA.
Zhongxue ChenDepartment of Mathematics and Statistics, College of Arts, Sciences and Education, Florida International University, Miami, Florida, USA.
Hannah J BlockDepartment of Kinesiology and College of Arts and Sciences, Indiana University, Bloomington, Indiana, USA.
Sharlene D NewmanAlabama Life Research Institute, College of Arts and Sciences, University of Alabama, Tuscaloosa, Alabama, USA.
Keisuke KawataDepartment of Kinesiology and College of Arts and Sciences, Indiana University, Bloomington, Indiana, USA.
Indiana University Bloomington · USEmory University · USFlorida International University · USUniversity of Alabama · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Subconcussive neurodegenerative progression in adolescent athletesR01NS113950 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI KAWATA, KEISUKE · 2021 to 2025
$2.8M
NCATS NIH HHS UL1 TR002529NINDS NIH HHS R01 NS113950
6 · The paper itself

Abstract

Recent investigations have identified water polo athletes as at risk for concussions and repetitive subconcussive head impacts. Head impact exposure in collegiate varsity women's water polo, however, has not yet been longitudinally quantified. We aimed to determine the relationship between cumulative and acute head impact exposure across pre-season training and changes in serum biomarkers of brain injury. Twenty-two Division I collegiate women's water polo players were included in this prospective observational study. They wore sensor-installed mouthguards during all practices and scrimmages during eight weeks of pre-season training. Serum samples were collected at six time points (at baseline, before and after scrimmages during weeks 4 and 7, and after the eight-week pre-season training period) and assayed for neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) using Simoa

Indexed as

Brain ConcussionFootballWater SportsAscorbic AcidBiomarkersFemaleGlial Fibrillary Acidic ProteinHumansIntermediate FilamentsProgesterone6-S-n-hexadecyl-3-O-methyl-6-thioascorbic acidAscorbic AcidBiomarkersGlial Fibrillary Acidic ProteinProgesteroneacute brain injuriesserum markerssports medicinesubconcussive head impactswater polo

Identifiers

PMID36259456
PMCPMC10266555
OpenAlexW4306782557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.