ArticleLaryngoscope investigative otolaryngology2022
Optimal timing of salvage intratympanic steroids in idiopathic sudden sensorineural hearing loss.
Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Salvage treatment strategies for refractory sudden sensorineural hearing loss-a comprehensive review and meta-analysis with practical recommendations.Frontiers in neurology · 2025Pooled it
- Efficacy of intratympanic methylprednisolone versus standard therapy in adult sudden sensorineural hearing loss.Frontiers in neurology · 2025Article
- Clinical efficacy of intratympanic steroid injection for treating idiopathic sudden sensorineural hearing loss.Journal of the Chinese Medical Association : JCMA · 2024Article
- Primary versus salvage intratympanic steroid treatment for idiopathic sudden sensorineural hearing loss.Laryngoscope investigative otolaryngology · 2023Article
- Optimal timing of salvage intratympanic steroids in idiopathic sudden sensorineural hearing loss.Laryngoscope investigative otolaryngology · 2022Article
- Quality evaluation of information about sudden sensorineural hearing loss on TikTok videos: Cross-sectional study.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Salvage intratympanic steroids (ITS) works in patients with idiopathic sudden sensorineural hearing loss (ISSNHL) after failure of initial therapy, but optimal timing of administration is unknown. Methods: Two hundred and seventy patients with ISSNHL were included. Among them, 180 were treated with ITS and standard medical treatment (SMT) and the other 90 received SMT along. The hearing threshold before and after salvage treatment were compared. The relationship between the salvage starting time and hearing recovery was analyzed. Results: The hearing of ITS group improved more than that of the SMT group in all frequency bands. The effect of both strategies decreases with the delay of the starting time. ITS can improve hearing even if being administrated 5 weeks after onset while SMT failed after 3 weeks. Conclusion: Patients with profound ISSNHL can obtain extra hearing recovery from salvage ITS. The earlier salvage starts, the greater the patient benefits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.