ArticleLaryngoscope investigative otolaryngology2022
Circulatory disturbance of the cochlear spiral modiolar artery in a type 2 diabetic mouse model.
Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Evaluation of hearing function in patients with type 2 diabetes mellitus and investigation of its relationship with stages of diabetic retinopathy.Journal of diabetes and metabolic disorders · 2025Article
- Association between subtypes of diabetes and special sensations: A 2-sample Mendelian randomization study.Medicine · 2025Article
- Diabetes mellitus and hearing loss.Molecular medicine (Cambridge, Mass.) · 2023Review
- Circulatory disturbance of the cochlear spiral modiolar artery in a type 2 diabetic mouse model.Laryngoscope investigative otolaryngology · 2022Article
- Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to identify significant differences in cochlea microvessel size between a diabetic mouse model (db/db) and normal mice using three-dimensional (3D) quantitative analysis. Methods: Six control heterozygote db/+ as well as 18 male B6/BKS(D)-Lepr Results: The average SMA-wall thickness in the db/db-mouse group (3.418 ± 0.328 μm) was greater than that in the control group (2.388 ± 0.411 μm). The average cross-sectional outer area, short diameter, and long diameter of the SMA in db/db mice were significantly larger than those in control mice (all Conclusion: The db/db mice had thicker and larger proximal-SMA vessel walls and diameters than control mice, respectively, thus potentially inducing increased blood viscosity or vascular insufficiency and aggravating hearing loss in type 2 diabetes mellitus. Level of Evidence: IIb.
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