Evidence map›Paper›PMID 36258794›Full record

ArticlePeerJ2022

Ribovirus classification by a polymerase barcode sequence.

Artem Babaian, Robert Edgar

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 76 citations in OpenAlex.

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  8. Mycoviruses confer hypovirulence but enhance antifungal volatile organic compound production in a phytopathogenic fungus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  15. Exploring the Structural Lexicon of the Proteome via Metric Geometry.bioRxiv : the preprint server for biology · 2025
    Article
  16. Discovery of a new konkovirus species inThe Journal of general virology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Artem Babaian *St Edmunds College, Cambridge, United Kingdom.
Robert Edgar *Corte Madera, California, United States of America.ORCID 0000-0001-7355-2541
University of Cambridge · GB

Funding

CIHR
6 · The paper itself

Abstract

RNA viruses encoding a polymerase gene (riboviruses) dominate the known eukaryotic virome. High-throughput sequencing is revealing a wealth of new riboviruses known only from sequence, precluding classification by traditional taxonomic methods. Sequence classification is often based on polymerase sequences, but standardised methods to support this approach are currently lacking. To address this need, we describe the polymerase palmprint, a segment of the palm sub-domain robustly delineated by well-conserved catalytic motifs. We present an algorithm, Palmscan, which identifies palmprints in nucleotide and amino acid sequences; PALMdb, a collection of palmprints derived from public sequence databases; and palmID, a public website implementing palmprint identification, search, and annotation. Together, these methods demonstrate a proof-of-concept workflow for high-throughput characterisation of RNA viruses, paving the path for the continued rapid growth in RNA virus discovery anticipated in the coming decade.

Indexed as

RNA VirusesAlgorithmsAmino Acid SequenceEukaryotaNucleotidyltransferasesNucleotidyltransferasesRNA-dependent RNA polymeraseRNA virusVirus classificationVirus evolution

Identifiers

PMID36258794
PMCPMC9573346
OpenAlexW4304889430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.