ReviewThe archives of bone and joint surgery2022
Intramedullary Nailing Versus Plate Fixation for Humeral Shaft Fractures: A Systematic Review and Meta-Analysis.
Review in The archives of bone and joint surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Systematic review of humeral shaft fracture (OTA/AO 12) complicated with iatrogenic radial nerve injury.European journal of medical research · 2024Pooled it
- Treatment of humeral shaft nonunion by exchange intramedullary nailing and circumferential cortical strut allograft: the Sarcophagus technique.JSES reviews, reports, and techniques · 2026Article
- InSafeLOCK intramedullary nailing versus plate fixation for humeral diaphyseal fractures: a retrospective cohort study with 24-month outcomes.BMC surgery · 2026Article
- Intramedullary nailing versus plate fixation for humeral shaft fractures in geriatric patients: a retrospective cohort study assessing functional outcomes and complication rates.BMC musculoskeletal disorders · 2025Article
- Intramedullary Nailing for Humeral Shaft Fractures: Functional Outcome Assessment Within a Cohort of 202 Patients.Journal of clinical medicine · 2025Article
- Nonunion and Postoperative Complications Associated With Intramedullary Nailing Versus Plate Fixation of Humeral Shaft Fractures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- [Conservative and operative treatment options for humeral shaft fractures].Unfallchirurgie (Heidelberg, Germany) · 2025Review
- Outcomes of intramedullary nailing versus plate fixation for humeral shaft fractures: a retrospective cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Article
- Comparative Study of Exchange Nailing and Augmentative Plating for Treating Aseptic Nonunion of Femoral Shafts Post Intramedullary Nailing: A Single-Blind, Multicentric Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Comparative outcomes of operative treatment for two and three-part proximal humerus fractures with or without ipsilateral shaft fractures and head-split patterns: intramedullary nail versus open reduction internal fixation.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Anterograde Intramedullary Nailing without Bone Grafting for Humeral Shaft Nonunion Associated with Early Exploration of Secondary Radial Nerve Palsy: A Case Report.Neurology international · 2024Article
- Short-term complication rates of open reduction and plate fixation and intramedullary nailing in the treatment of humeral shaft fractures: a propensity score matched analysis.Archives of orthopaedic and trauma surgery · 2024Article
- Correlation between Peripheric Blood Markers and Surgical Invasiveness during Humeral Shaft Fracture Osteosynthesis in Young and Middle-Aged Patients.Diagnostics (Basel, Switzerland) · 2024Article
- Extra-Articular Distal Humerus Plate 3D Model Creation by Using the Method of Anatomical Features.Materials (Basel, Switzerland) · 2023Article
- Treatment of humeral shaft fractures with different treatment methods: a network meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The two techniques most utilized in the surgical treatment of humeral shaft fractures are open reduction internal fixation (ORIF) and intramedullary nailing (IMN). Although there have been multiple comparative clinical studies comparing outcomes for these two treatments, studies have not suggested one approach to be superior to the other. The purpose of this study is to perform a systematic literature review and meta-analysis of studies that evaluated the treatment of humeral shaft fractures with either ORIF or intramedullary nail. Methods: We conducted this meta-analysis utilizing stricter inclusion and broader exclusion criteria to examine these two common approaches. We examined those articles which have compared first-time, closed fractures of the humeral diaphysis in adults in fracture patterns that could be treated equivalently by intramedullary nail or plate fixation. The primary outcome of interest was nonunion, and studies that did not report nonunion rates were excluded. Results: There were a total of 1,926 abstracts reviewed and a total of three articles were included in the final analysis after screening. There was no significant difference in the incidence of nonunion between plating (2/111, 1.8%) and nailing (4/104, 3.9%) ( Conclusion: The results of this analysis demonstrate an increased risk of iatrogenic radial nerve injury, and a significantly shorter time to union when treating humeral shaft fractures with plating as compared to intramedullary nailing. There was no difference in the rates of nonunion or delayed union. Based on the evidence, both plating and nailing can achieve a similar treatment effect on humeral shaft fractures.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.