Evidence map›Paper›PMID 36258218›Full record

ArticleBMC medical informatics and decision making2022

Natural language processing for identification of hypertrophic cardiomyopathy patients from cardiac magnetic resonance reports.

Nakeya Dewaswala, David Chen, Huzefa Bhopalwala, Vinod C Kaggal, Sean P Murphy, J Martijn Bos, Jeffrey B Geske, Bernard J Gersh, Steve R Ommen, Philip A Araoz and 2 more

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Artificial Intelligence Large Language Models in Cardiology.Reviews in cardiovascular medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nakeya Dewaswala *Department of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
David Chen *Department of Cardiovascular Surgery, Cleveland Clinic, OH, Cleveland, USA.
Huzefa BhopalwalaDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Vinod C KaggalEnterprise Technology Services, Shared Service Offices, Mayo Clinic, MN, Rochester, USA.
Sean P MurphyAdvanced Analytics Services, Mayo Clinic Rochester, Rochester, MN, USA.
J Martijn BosDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Jeffrey B GeskeDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Bernard J GershDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Steve R OmmenDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Philip A AraozDepartment of Radiology, Mayo Clinic Rochester, Rochester, MN, USA.
Michael J AckermanDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.
Adelaide M Arruda-OlsonDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA. ArrudaOlson.Adelaide@mayo.edu.

Funding

Novel Informatics Approaches for Ascertainment of PAD Status and Adverse OutcomesK01HL124045 · NHLBI · MAYO CLINIC ROCHESTER · PI ARRUDA-OLSON, ADELAIDE MARIA MARTINS · 2015 to 2019
$820k
NHLBI NIH HHS K01 HL124045
6 · The paper itself

Abstract

backgroundCardiac magnetic resonance (CMR) imaging is important for diagnosis and risk stratification of hypertrophic cardiomyopathy (HCM) patients. However, collection of information from large numbers of CMR reports by manual review is time-consuming, error-prone and costly. Natural language processing (NLP) is an artificial intelligence method for automated extraction of information from narrative text including text in CMR reports in electronic health records (EHR). Our objective was to assess whether NLP can accurately extract diagnosis of HCM from CMR reports.

methodsAn NLP system with two tiers was developed for information extraction from narrative text in CMR reports; the first tier extracted information regarding HCM diagnosis while the second extracted categorical and numeric concepts for HCM classification. We randomly allocated 200 HCM patients with CMR reports from 2004 to 2018 into training (100 patients with 185 CMR reports) and testing sets (100 patients with 206 reports).

resultsNLP algorithms demonstrated very high performance compared to manual annotation. The algorithm to extract HCM diagnosis had accuracy of 0.99. The accuracy for categorical concepts included HCM morphologic subtype 0.99, systolic anterior motion of the mitral valve 0.96, mitral regurgitation 0.93, left ventricular (LV) obstruction 0.94, location of obstruction 0.92, apical pouch 0.98, LV delayed enhancement 0.93, left atrial enlargement 0.99 and right atrial enlargement 0.98. Accuracy for numeric concepts included maximal LV wall thickness 0.96, LV mass 0.99, LV mass index 0.98, LV ejection fraction 0.98 and right ventricular ejection fraction 0.99.

conclusionsNLP identified and classified HCM from CMR narrative text reports with very high performance.

Indexed as

Cardiomyopathy, HypertrophicNatural Language ProcessingArtificial IntelligenceHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyStroke VolumeVentricular Function, RightCardiac magnetic resonance imagingHypertrophic cardiomyopathyNatural language processingRadiology reports

Identifiers

PMID36258218
PMCPMC9580188

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.