ArticleRespiratory research2022
Association between exercise and risk of cardiovascular diseases in patients with non-cystic fibrosis bronchiectasis.
Article in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- Incidence and disease burden of bronchiectasis in systemic lupus erythematosus: a nationwide population-based study in Korea.RMD open · 2026Article
- Effect of COVID-19 vaccination and SARS-CoV-2 infection status on mortality risk in patients with chronic obstructive pulmonary disease: a nationwide population-based cohort study.Respiratory research · 2026Article
- Association between gastroesophageal reflux disease and incident bronchiectasis: a nationwide representative population-based study in Korea.BMC pulmonary medicine · 2025Article
- Risk of Stroke in COVID-19 Survivors With Asthma: A Nationwide, Population-Based Cohort Study.Journal of Korean medical science · 2025Article
- Effects of Vaccination on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Cohort Study.Tuberculosis and respiratory diseases · 2025Article
- Addressing treatable traits in bronchiectasis through non-pharmacological therapies: a narrative review.Journal of thoracic disease · 2025Review
- Exacerbation and mortality risk in individuals with bronchiectasis post-COVID-19 recovery.ERJ open research · 2025Article
- Risk of acute exacerbation of chronic obstructive pulmonary disease after COVID-19 recovery: a nationwide population-based cohort study.Respiratory research · 2025Article
- Sex-Specific Multimorbidity-Multibehaviour Patterns in Primary Care Populations.International journal of environmental research and public health · 2025Observational
- Article
- COVID-19 and risk of long-term mortality in COPD: a nationwide population-based cohort study.BMJ open respiratory research · 2025Article
- Association of lifestyle change after H. pylori eradication with cardiovascular disease: a nationwide Korean NHIS cohort study.BMJ public health · 2025Article
- Impact of physical activity on all-cause mortality in individuals with non-cystic fibrosis bronchiectasis.Frontiers in medicine · 2025Article
- Severe bronchiectasis is associated with increased carotid intima-media thickness.BMC cardiovascular disorders · 2024Article
- Big Data Research on Severe Asthma.Tuberculosis and respiratory diseases · 2024Article
- Analysis of clinical characteristics, prognosis and influencing factors in patients with bronchiectasis-chronic obstructive pulmonary disease overlap syndrome: A prospective study for more than five years.Journal of global health · 2024Article
- Bronchiectasis management in adults: state of the art and future directions.The European respiratory journal · 2024Review
- Increased Risk of Incident Chronic Obstructive Pulmonary Disease and Related Hospitalizations in Tuberculosis Survivors: A Population-Based Matched Cohort Study.Journal of Korean medical science · 2024Article
- Impacts of regular physical activity on hospitalisation in chronic obstructive pulmonary disease: a nationwide population-based study.BMJ open respiratory research · 2024Article
- Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study.Arthritis research & therapy · 2023Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAlthough cardiovascular comorbidities negatively impact survival in patients with bronchiectasis, there is limited evidence to recommend exercise in this population. We aimed to evaluate whether exercise habit changes are related to reduced cardiovascular disease risk and explore an optimal exercise amount.
methodsThis study identified 165,842 patients with newly diagnosed bronchiectasis during 2010-2016 who underwent two health examinations and were followed up until December 2020. The exposure was the change in weekly habits of moderate- or vigorous-intensity physical activity between the two examinations, classified into non-exercisers and exercisers (further classified into new exercisers, exercise dropouts, and exercise maintainers). The amount of exercise was measured using metabolic equivalents of task (MET). The outcome was the incidence of myocardial infarction (MI) or stroke.
resultsDuring a mean of 6.2 ± 2.1 follow-up years, 4,233 (2.6%) and 3,745 (2.3%) of patients with bronchiectasis had MI or stroke, respectively. Compared to non-exercisers, exercisers had a significantly lower risk of MI or stroke by 9-28% (p < 0.001 for both). Among exercisers, exercise maintainers showed the lowest risk of MI (adjusted hazard ratio [aHR], 0.72; 95% confidence interval [CI], 0.64-0.81) and stroke (aHR, 0.72; 95% CI, 0.64-0.82) compared to non-exercisers. Regarding exercise amount, a significant risk reduction was observed only in patients with bronchiectasis who exercised for ≥ 500 MET-min/wk.
conclusionExercise was associated with a reduced risk of cardiovascular diseases in patients with bronchiectasis. In particular, the risk was lowest in exercise maintainers, and cardiovascular risk reduction was significant when exercising more than 500 MET-min/wk.
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