Evidence map›Paper›PMID 36258183›Full record

Trial reportBMC nephrology2022

Prognostic significance of malnutrition risk in elderly patients with acute kidney injury in the intensive care unit.

Na Wang, Ping Wang, Wen Li, Li Jiang, Meiping Wang, Bo Zhu, Xiuming Xi

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bayesian Analysis of Modified Nutrition Risk in Critically Ill (mNUTRIC) Score for Mortality Prediction in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  7. Article
  8. Article
  9. Modified NUTRIC Score as a Predictor of All-cause Mortality in Critically Ill Patients: A Systematic Review and Meta-analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Na Wang *Emergency department of China rehabilitation research center, Capital Medical University, no.10 Jiaomen north Street, Fengtai District, Beijing, 100068, China.
Ping Wang *Emergency department of Fu Xing Hospital, Capital Medical University, no. 20 Fuxingmenwai Street, Xicheng District, Beijing, 100038, China.
Wen LiDepartment of Critical Care Medicine, Peking University Third Hospital, no. 49 Huayuan north Street, Haidian District, Beijing, 100191, China.
Li JiangDepartment of Critical Care Medicine, Xuan Wu Hospital, Capital Medical University, no. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Meiping WangDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, no.10 Xitoutiao, Youanmen, Fengtai District, Beijing, 100069, China.
Bo ZhuDepartment of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, no. 20 Fuxingmenwai Street, Xicheng District, Beijing, 100038, China.
Xiuming XiDepartment of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, no. 20 Fuxingmenwai Street, Xicheng District, Beijing, 100038, China. xixiuming2937@sina.com.
Capital Medical University · CNChina Rehabilitation Research Center · CNPeking University Third Hospital · CNXuan Wu Hospital of the Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition is common in critically ill patients, but nutrition status in critically ill patients with acute kidney injury (AKI) has been poorly studied. Our study aimed to investigate the relationship between malnutrition risk and the occurrence and prognosis of AKI in elderly patients in the intensive care unit (ICU).

methodsData were extracted from the Beijing Acute Kidney Injury Trial (BAKIT). A total of 1873 elderly patients were included and compared according to the clinical characteristics of AKI and non-AKI groups, and those of survivors and non-survivors of AKI in this study. Receiver operating characteristic (ROC) curves were used to analyse the predictive value of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for the occurrence and 28-day prognosis of AKI. Multivariate Cox regression analysis was used to evaluate the effect of the mNUTRIC score on the 28-day mortality in AKI patients.

resultsCompared with the non-AKI group, AKI patients had higher mNUTRIC scores, and non-survivors had higher mNUTRIC scores than survivors in AKI population. Moreover, multivariate Cox regression showed that 28-day mortality in AKI patients increased by 9.8% (95% CI, 1.018-1.184) for every point increase in the mNUTRIC score, and the mNUTRIC score had good predictive ability for the occurrence of AKI and 28-day mortality in AKI patients. The mortality of AKI patients with mNUTRIC > 4 was significantly increased.

conclusionsThe elderly patients are at high risk of malnutrition, which affects the occurrence and prognosis of AKI. Adequate attention should be given to the nutritional status of elderly patients.

trial registrationThis study was registered at www.chictr.org.cn (registration number Chi CTR-ONC-11001875) on 14 December 2011.

Indexed as

Acute Kidney InjuryMalnutritionAgedCritical IllnessHumansIntensive Care UnitsPrognosisAKIElderly patientMalnutrition riskmNUTRICPrognosis

Identifiers

PMID36258183
PMCPMC9578231
OpenAlexW4306690366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.