Boronates as hydrogen peroxide-reactive warheads in the design of detection probes, prodrugs, and nanomedicines used in tumors and other diseases.

Jyun-Wei Chen, Tzu-Chien Wu, Wun Liang, Jyun-Jia Ciou, Chian-Hui Lai

Abstract readReview

In one paragraph

Review in Drug delivery and translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

2.6field-weighted citation impact, top 9% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 24 citations in OpenAlex.

A Prodrug Approach for Activity-Based Chemical Modulation toward Multiple Pathological Targets in Alzheimer's Disease.Small (Weinheim an der Bergstrasse, Germany) · 2026
Article
Design, Synthesis of Hydrogen Peroxide Response AIE Fluorescence Probes Based on Imidazo [1,2-a] Pyridine.Molecules (Basel, Switzerland) · 2024
Article
A selective fluorescent turn-on probe for imaging and sensing of hydrogen peroxide in living cells.Analytical and bioanalytical chemistry · 2023
Article
The Challenging Treatment of Cisplatin-Resistant Tumors: State of the Art and Future Perspectives.Molecules (Basel, Switzerland) · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jyun-Wei Chen *Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 40227, Taiwan.

Tzu-Chien Wu *Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 40227, Taiwan.

Wun Liang *Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 40227, Taiwan.

Jyun-Jia CiouGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 40227, Taiwan.

Chian-Hui LaiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 40227, Taiwan. chianhuilai@dragon.nchu.edu.tw.ORCID 0000-0002-2697-4845

National Chung Hsing University · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

NeoplasmsProdrugsFluorescent DyesHumansHydrogen PeroxideNanomedicineProspective StudiesReactive Oxygen SpeciesFluorescent DyesHydrogen PeroxideProdrugsReactive Oxygen SpeciesBoronate-based probesCell imagingElectrochemical biosensorsHydrogen peroxideNanomedicinesProdrugsReactive oxygen species

Identifiers

PMID36258159

DOI10.1007/s13346-022-01248-w

OpenAlexW4306720302

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.