Evidence map›Paper›PMID 36258030›Full record

ArticleScientific reports2022

Interpregnancy interval and maternal and neonatal morbidity: a nationwide cohort study.

Hanna Mühlrad, Evelina Björkegren, Philip Haraldson, Nina Bohm-Starke, Helena Kopp Kallner, Sophia Brismar Wendel

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Interpregnancy intervals and maternal and neonatal outcomes: A retrospective cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanna MühlradDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden. hanna.muhlrad@ki.se.
Evelina BjörkegrenDepartment of Economics, Stockholm University, Stockholm, Sweden.
Philip HaraldsonDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Nina Bohm-StarkeDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Helena Kopp KallnerDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Sophia Brismar WendelDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the association between interpregnancy interval (IPI)-the time from childbirth to conception of the next pregnancy-and maternal and neonatal morbidity. The World Health Organization (WHO) currently recommends an IPI of at least 24 months after a live birth to reduce adverse birth outcomes. However, assessing the relationship between IPI and perinatal outcome is complicated by confounding factors. We conducted a nationwide population-based cohort study using Swedish registry data, allowing for adjustment of maternal characteristics and health at first birth. The study population consisted of all women with a singleton, live, and vaginal first birth with a second singleton birth within five years during 1997-2017, covering 327,912 women and 655,824 neonates. IPI was grouped into six-month intervals with 24-29 months as the reference. The association between IPI and morbidity was examined using multivariate logistic regression. For women having a vaginal delivery at their first birth, intervals < 24-29 months were associated with decreased maternal morbidity and unaffected neonatal morbidity. Intervals > 24-29 months were associated with increased maternal and neonatal morbidity. Our findings question the relevance of WHO's recommendation of an IPI of at least 24 months in a high-income country.

Indexed as

Birth IntervalsPregnancy ComplicationsCohort StudiesFemaleHumansInfant, NewbornLive BirthLogistic ModelsMaternal AgePregnancyRetrospective StudiesRisk Factors

Identifiers

PMID36258030
PMCPMC9579163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.