Evidence map›Paper›PMID 36256828›Full record

ArticleJournal of medical Internet research2021

Human Enough: A Qualitative Study of Client Experience With Internet-Based Access to Pre-exposure Prophylaxis.

Shana D Hughes, Kimberly A Koester, Edvard Engesaeth, Merissa V Hawkins, Robert M Grant

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. User Input in the Development of Digital Sexual Health Tools: A Scoping Review and Guidance for Tool Developers.Health expectations : an international journal of public participation in health care and health policy · 2025
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  14. Strategies to Eliminate Inequity in PrEP Services in the US South and Rural Communities.The Journal of the Association of Nurses in AIDS Care : JANAC
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shana D HughesDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.ORCID 0000-0002-1388-4103
Kimberly A KoesterDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.ORCID 0000-0003-0023-1127
Edvard EngesaethNurx, San Francisco, CA, United States.ORCID 0000-0003-0348-1826
Merissa V HawkinsNurx, San Francisco, CA, United States.ORCID 0000-0001-8312-580X
Robert M GrantDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.ORCID 0000-0002-0851-7085
University of California, San Francisco · USNurix (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV pre-exposure prophylaxis (PrEP) is a way to prevent HIV infection using antiretroviral medications. However, common barriers to PrEP engagement include lack of access to prescribers; discomfort seeking sexual health services; and racism, homophobia, and transphobia in medical contexts. Key populations (eg, communities of color, young men who have sex with men, and transgender women) are underrepresented in terms of PrEP uptake in the United States. Nurx is an innovative company that has offered internet-based access to PrEP since 2016.

objectiveIn this study, in partnership with Nurx, we aim to explore clients' experiences of digital PrEP access-including the difference made by the telehealth format-and to understand whether Nurx helped reduce barriers to PrEP.

methodsElectronic chart review and semistructured interviews were conducted with 31 PrEP requesters from California, Florida, Illinois, and New York. Interviews were recorded, transcribed, and subjected to inductive and deductive thematic analysis.

resultsSome interviewees reported initial skepticism about whether a web-based PrEP service could be legitimate or feasible. Despite this, most clients were effusive about their eventual Nurx experience, and many reported that Nurx eased barriers to PrEP access through the availability of knowledgeable, willing prescribers and minimizing embarrassment and discrimination. Our analysis suggests Nurx produced satisfaction by achieving an acceptable balance between 2 client desires: efficiency and humanity. Efficiency encompasses the simplicity, speed, and convenience of obtaining PrEP, both regarding the Nurx process itself and in comparison with in-person encounters. Humanity covers clients' wish for personalized, responsive interaction and a feeling of connection or care. Nurx's messaging platform was crucial to manifesting these qualities and was largely interpreted through the familiar frame of texting. Clients conceived efficiency and humanity as inversely related in a commercial enterprise and varied in the particular balance they felt was optimal. Those who wished for slightly more humanity than the service afforded used the concept of a trade-off to explain why Nurx remained appealing.

conclusionsOur findings augment evidence that internet-based PrEP provision can broaden access to this HIV prevention strategy. This important finding, notwithstanding a few provisos, merits mention. Telehealth, as practiced by Nurx, was still dependent on culturally competent medical providers as system inputs, and the very technology used to overcome access barriers (ie, the internet) generated new hurdles for some clients. Furthermore, clients did not interpret Nurx in a vacuum: their past experiences and the social and structural context mattered. Finally, only granular inquiry revealed precisely how Nurx satisfied clients whose experiences and preferences fell within a particular range. Extrapolating from this, we urge scholars not to fetishize technological solutions but rather to interrogate the ways in which any intervention's design works for certain kinds of patients.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesFemaleHomosexuality, MaleHumansInternetMaleUnited StatesAnti-HIV Agentsclient/user experienceHIVinternetpre-exposure prophylaxis (PrEP)qualitativetelehealth

Identifiers

PMID36256828
PMCPMC8406118
OpenAlexW3142208996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.