Evidence map›Paper›PMID 36256825›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Lysosomal positioning regulates Rab10 phosphorylation at LRRK2

Jillian H Kluss, Alexandra Beilina, Chad D Williamson, Patrick A Lewis, Mark R Cookson, Luis Bonet-Ponce

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  6. Rab10 plays a protective role in the development of pathological cardiac hypertrophy.Journal of molecular and cellular cardiology plus · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jillian H KlussCell Biology and Gene Expression Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.
Alexandra BeilinaCell Biology and Gene Expression Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.
Chad D WilliamsonCell Biology and Neurobiology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Patrick A LewisSchool of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6AH, United Kingdom.ORCID 0000-0003-4537-0489
Mark R CooksonCell Biology and Gene Expression Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.
Luis Bonet-PonceCell Biology and Gene Expression Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0001-9276-059X
National Institutes of Health · USRoyal Veterinary College · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic variation at the

Indexed as

Lysosomesrab GTP-Binding ProteinsLeucineLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MutationPhosphoric Monoester HydrolasesPhosphorylationLeucineLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Phosphoric Monoester Hydrolasesrab GTP-Binding ProteinsJIP4kinaseLLOMeLYTLParkinson's disease

Identifiers

PMID36256825
PMCPMC9618077
OpenAlexW4306734767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.