Evidence map›Paper›PMID 36256819›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Loss of

Ya-Ting Chang, Max Kowalczyk, P Michelle Fogerson, Yu-Ju Lee, Minza Haque, Eliza L Adams, David C Wang, Laura A DeNardo, Marc Tessier-Lavigne, John R Huguenard and 2 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  12. Loss ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Ya-Ting ChangDepartment of Neurology and Neurosurgery, Centre for Research in Neuroscience, McGill University, QC, H3G 1A3, Canada.
Max KowalczykDepartment of Neurology and Neurosurgery, Centre for Research in Neuroscience, McGill University, QC, H3G 1A3, Canada.
P Michelle FogersonDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.
Yu-Ju LeeDepartment of Neurology and Neurosurgery, Centre for Research in Neuroscience, McGill University, QC, H3G 1A3, Canada.ORCID 0000-0002-5319-7498
Minza HaqueDepartment of Neurology and Neurosurgery, Centre for Research in Neuroscience, McGill University, QC, H3G 1A3, Canada.
Eliza L AdamsDepartment of Biology, Stanford University, Stanford, CA 94305.
David C WangDepartment of Biology, Stanford University, Stanford, CA 94305.
Laura A DeNardoDepartment of Biology, Stanford University, Stanford, CA 94305.
Marc Tessier-LavigneDepartment of Biology, Stanford University, Stanford, CA 94305.
John R HuguenardDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.
Liqun LuoDepartment of Biology, Stanford University, Stanford, CA 94305.ORCID 0000-0001-5467-9264
Wei-Hsiang HuangDepartment of Neurology and Neurosurgery, Centre for Research in Neuroscience, McGill University, QC, H3G 1A3, Canada.
Stanford University · USMcGill University Health Centre · CA

Funding

Inhibitory Controls of Thalamic NeuronsR01NS034774 · NINDS · STANFORD UNIVERSITY · PI HUGUENARD, JOHN R · 1996 to 2021
$5.5M
Tracking pre-seizure dynamics to predict and control seizuresR01NS117150 · NINDS · STANFORD UNIVERSITY · PI GANGULI, SURYA, HUGUENARD, JOHN R · 2020 to 2024
$2.1M
NINDS NIH HHS R01 NS034774NINDS NIH HHS R01 NS117150
6 · The paper itself

Abstract

Hyperexcitability of brain circuits is a common feature of autism spectrum disorders (ASDs). Genetic deletion of a chromatin-binding protein,

Indexed as

Smith-Magenis SyndromeAnimalsChromatinDisease Models, AnimalHippocampusMicePhenotypeSeizuresTrans-ActivatorsTretinoinChromatinRai1 protein, mouseTrans-ActivatorsTretinoinautism spectrum disordersdentate gyrusneuronal excitabilitySmith–Magenis syndromewhole-brain clearing and imaging

Identifiers

PMID36256819
PMCPMC9618093
OpenAlexW4306734809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.