Evidence map›Paper›PMID 36256814›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Structural and functional investigation of ABC transporter STE6-2p from

E Sabine M Schleker, Sabine Buschmann, Hao Xie, Sonja Welsch, Hartmut Michel, Christoph Reinhart

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E Sabine M SchlekerDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0003-2219-3096
Sabine BuschmannDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0003-0430-4477
Hao XieDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0002-2422-2527
Sonja WelschCentral Electron Microscopy Facility, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0002-6049-6664
Hartmut MichelDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0003-4351-7846
Christoph ReinhartDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany.ORCID 0000-0002-3580-1807
Max Planck Institute of Biophysics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are multidomain transmembrane proteins, which facilitate the transport of various substances across cell membranes using energy derived from ATP hydrolysis. They are important drug targets since they mediate decreased drug susceptibility during pharmacological treatments. For the methylotrophic yeast

Indexed as

ATP-Binding Cassette TransportersSterolsAdenosine TriphosphateAdenylyl ImidodiphosphateHumansPhylogenyRhodaminesSaccharomyces cerevisiaeSaccharomycetalesTriazolesVerapamilAdenosine TriphosphateAdenylyl ImidodiphosphateATP-Binding Cassette TransportersRhodaminesSterolsTriazolesVerapamilABC transportermultidrug resistanceprotein–sterol interactionverapamilyeast transport assay

Identifiers

PMID36256814
PMCPMC9618074
OpenAlexW4306734834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.