Evidence map›Paper›PMID 36255613›Full record

ArticleInternational ophthalmology2023

Prevalence of Demodex folliculorum and Demodex brevis in patients with blepharitis and chalazion.

Serife Akkucuk, Ozlem Makbule Kaya, Lokman Aslan, Talat Ozdemir, Ugur Uslu

Abstract read
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In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Pathogens (Basel, Switzerland) · 2025
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  4. Significance ofMedicina (Kaunas, Lithuania) · 2025
    Review
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  6. A new digital biomarker ofFrontiers in cell and developmental biology · 2025
    Article
  7. Article
  8. The Prevalence ofLife (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Serife AkkucukDepartment of Parasitology, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey. serifeakkucuk@hotmail.com.
Ozlem Makbule KayaDepartment of Parasitology, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey.
Lokman AslanDepartment of Ophthalmology, Private Sevgi Hospital, Osmaniye, Turkey.
Talat OzdemirDepartment of Ophthalmology, Private Sevgi Hospital, Osmaniye, Turkey.
Ugur UsluDepartment of Microbiology, Faculty of Medicine, Selcuk University, Konya, Turkey.
Mustafa Kemal University · TRSema Hospital · TRSelçuk University · TR

Funding

Mustafa Kemal Üniversitesi 18.D.013
6 · The paper itself

Abstract

purposeDemodex folliculorum and Demodex brevis are common ectoparasites on skin that also can lead to blepharitis and chalazion. The aim of our study is to determine the prevalence of Demodex spp. in eyelashes of patients diagnosed with chronic blepharitis and chalazion.

methodsThis study included 330 patients diagnosed with chronic blepharitis, 70 patients diagnosed with chalazion and 130 volunteers without any ocular problems. Patient eyelashes were examined under a light microscope at magnifications of × 40, × 100 and × 400. Demodex spp. were determined.

resultsParasite prevalence was significantly higher in blepharitis (75.5%) and chalazion groups (70%) compared to the control group (16.2%) (p < 0.001). The prevalence of D. folliculorum in the blepharitis group and D. brevis in the chalazion group was found to be significantly higher compared to other groups (p < 0.05). The average number of mites per eyelash was found to be significantly higher in patients with Demodex positive blepharitis (p = 0.001) and in chalazion patients (p = 0.047) than in the control group. It has been determined that mite positivity increases with age in blepharitis and control groups (p < 0.05). In the group with blepharitis, it was found that mite positivity was significant in the presence of symptoms (p = 0.0001) and Demodex positivity decreased as the education level of individuals increased (p = 0.039).

conclusionThe results of the study show that Demodex spp infestations should be considered in chronic blepharitis and chalazion.

Indexed as

AscomycotaBlepharitisChalazionEye Infections, ParasiticEyelashesMite InfestationsMitesAnimalsChronic DiseaseHumansPrevalenceBlepharitisChalazionDemodex brevisDemodex folliculorumEyelash

Identifiers

PMID36255613
OpenAlexW4306733421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.