Evidence map›Paper›PMID 36255496›Full record

ArticleMikrochimica acta2022

A "signal-on" photoelectrochemical sensor for human epidermal growth factor receptor 2 detection based on Y6/CdS organic-inorganic heterojunction.

Jiarong Luo, Junjun Luo, Lei Deng, Minghui Yang, Xiang Chen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiarong LuoHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China.
Junjun LuoSchool of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Lei DengHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China.
Minghui YangHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China. yangminghui@csu.edu.cn.ORCID http://orcid.org/0000-0002-7612-8137
Xiang ChenSchool of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, China. chenxiangck@126.com.
Central South University · CN

Funding

Hunan Provincial Science and Technology Department 2019TP1001Ministry of Industry and Information Technology of the People's Republic of China TC210804VNational Natural Science Foundation of China 22174163
6 · The paper itself

Abstract

A "signal-on" photoelectrochemical (PEC) immunosensor was successfully constructed for determination of human epidermal growth factor receptor 2 (HER2) based on organic-inorganic heterojunction Y6/CdS as photoactive material. Compared with single organic semiconductor, Y6, Y6/CdS exhibited higher photoelectric conversion efficiency due to the formation of heterojunction. In the presence of HER2, sandwich immune structure was formed between HER2 aptamer and anti-HER2 antibody (Ab) by specific recognition. The polydopamine (PDA) nanoparticles were used for signal amplification to enhance photocurrent intensity as PDA can act as electron donor to eliminate holes and promote electron-hole pairs separation. The developed PEC sensor displayed a wide detection range of 5-1000 pg mL

Indexed as

Biosensing TechniquesCadmium CompoundsElectrochemical TechniquesErb-b2 Receptor Tyrosine KinasesHumansImmunoassayLimit of DetectionReproducibility of ResultsCadmium CompoundsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesHuman epidermal growth factor receptor 2ImmunosensorOrganic–inorganic heterojunctionPhotoelectrochemicalPolydopamine

Identifiers

PMID36255496
OpenAlexW4306698395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.