ArticleMagnetic resonance in medicine2023
Time-encoded pseudo-continuous arterial spin labeling: Increasing SNR in ASL dynamic angiography.
Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Dynamic pseudo-continuous arterial spin labeling angiography using a 3D-radial multi-spoke spoiled gradient-recalled sequence.Magnetic resonance in medicine · 2026Article
- Combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast.Magnetic resonance in medicine · 2026Article
- Prognostic Utility of Arterial Spin Labeling in Traumatic Brain Injury: From Pathophysiology to Precision Imaging.NeuroSci · 2025Review
- Ultra-high temporal resolution 4D angiography using arterial spin labeling with subspace reconstruction.Magnetic resonance in medicine · 2025Article
- Transformer-based deep learning denoising of single and multi-delay 3D arterial spin labeling.Magnetic resonance in medicine · 2024Article
- Optimization of 4D combined angiography and perfusion using radial imaging and arterial spin labeling.Magnetic resonance in medicine · 2023Article
- Time-encoded pseudo-continuous arterial spin labeling: Increasing SNR in ASL dynamic angiography.Magnetic resonance in medicine · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeDynamic angiography using arterial spin labeling (ASL) can provide detailed hemodynamic information. However, the long time-resolved readouts require small flip angles to preserve ASL signal for later timepoints, limiting SNR. By using time-encoded ASL to generate temporal information, the readout can be shortened. Here, the SNR improvements from using larger flip angles, made possible by the shorter readout, are quantitatively investigated.
methodsThe SNR of a conventional protocol with nine Look-Locker readouts and a 4
resultsThe time-encoded protocol increased in vivo SNR by 103% and 96% when using CFAs or VFAs, respectively. Use of VFAs improved SNR compared with CFAs by 25% and 21% for the conventional and time-encoded protocols, respectively. The VFA scheme also removed signal discontinuities in the time-encoded data. Preliminary data suggest that optimizing the background suppression could improve in vivo SNR by a further 16%.
conclusionsTime encoding can be used to generate additional temporal information in ASL angiography. This enables the use of larger flip angles, which can double the SNR compared with a non-time-encoded protocol. The shortened time-encoded readout can also lead to improved background suppression, reducing physiological noise and further improving SNR.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.