ArticleMagnetic resonance in medicine2023
Multi-modal MRI reveals changes in placental function following preterm premature rupture of membranes.
Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Placental multimodal MRI prior to spontaneous preterm birth <32 weeks' gestation: An observational study.BJOG : an international journal of obstetrics and gynaecology · 2024Observational
- Sensitivity analysis of transabdominal fetal pulse oximetry using MRI-based simulations.Biomedical optics express · 2024Article
- The Fetal Spleen in Low-Risk Pregnancies and prior to Preterm Birth: Observational Study of the Role of Anatomical and Functional Magnetic Resonance Imaging.Fetal diagnosis and therapy · 2024Observational
- Multi-modal MRI reveals changes in placental function following preterm premature rupture of membranes.Magnetic resonance in medicine · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposePreterm premature rupture of membranes complicates up to 40% of premature deliveries. Fetal infection may occur in the absence of maternal symptoms, delaying diagnosis and increasing morbidity and mortality. A noninvasive antenatal assessment of early signs of placental inflammation is therefore urgently required.
methodsSixteen women with preterm premature rupture of membranes < 34 weeks gestation and 60 women with uncomplicated pregnancies were prospectively recruited. A modified diffusion-weighted spin-echo single shot EPI sequence with a diffusion preparation acquiring 264 unique parameter combinations in < 9 min was obtained on a clinical 3 Tesla MRI scanner. The data was fitted to a 2-compartment
resultsPlacental
conclusionMore complex models and data acquisition can potentially improve fitting of the underlying etiology of preterm birth compared with individual single-contrast models and contribute to additional insights in the future. This will need validation in larger cohorts. A multi-modal MRI acquisition between rupture of the membranes and delivery can be used to measure placental function and is linked to gestational age at delivery.
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