Evidence map›Paper›PMID 36254929›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia.

Georgios Zacharakis, Abdulaziz Almasoud, Omar Arahmaner, Khaled Aldossary, Jamaan Alzahrani, Sameer Al-Ghamdi, Abdullah AlShehri, Pavlos Nikolaidis, Abdullah Bawazir, Talal Alfayez and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. A chain is only as strong as its weakest link: Care pathways in colorectal cancer, from emergency interventions to preventive strategies.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Doing things right and doing the right things: Colorectal cancer screening in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Georgios ZacharakisDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Abdulaziz AlmasoudDepartment of Gastroenterology, Prince Sultan Military Medical City, Riyadh; Endoscopy Unit, Al-Kharj Military Hospital, Al-Kharj, Saudi Arabia.
Omar ArahmanerEndoscopy Unit, King Khaled Hospital and Prince Sultan Centre for Health Care, Al-Kharj, Saudi Arabia.
Khaled AldossaryDepartment of Family and Community Medicine, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Jamaan AlzahraniDepartment of Family and Community Medicine, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Sameer Al-GhamdiDepartment of Family and Community Medicine, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Abdullah AlShehriDepartment of Family Medicine, Al-Kharj Military Hospital, Al-Kharj, Saudi Arabia.
Pavlos NikolaidisCollege of Computer and Information Sciences, Al-Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Abdullah BawazirDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Talal AlfayezDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Moataz DaadourDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Faisal AlslimahDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Mohammed AltamimiDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Sami AlshalawiDepartment of Internal Medicine, Division of Gastroenterology, College of Medicine, Prince Sattam Bin, Abdulaziz University, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Saudi Arabia.
Prince Sattam Bin Abdulaziz University · SAImam Mohammad ibn Saud Islamic University · SAKing Khaled Hospital · SARiyadh Armed Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Al-Kharj colorectal cancer (CRC) screening program was implemented for five years (2017-2022) in a central urban area of Riyadh Province, Saudi Arabia, to assess the participation and impact of the program in average-risk individuals. Methods: The high sensitivity-guaiac based-fecal occult blood test (HSgFOBT) was used as a first-line investigation to identify asymptomatic patients, aged 45-75 years, requiring CRC screening using colonoscopy. The program was run in three tertiary hospitals in the area. Results: The five-year participation rate was 73% (35,640/48,897). The average age was 53 years (range 45-75), 49% were female (17,464/35,640), all were asymptomatic, and 77% had adequate bowel preparation. The HSgFOBT (+) rate was 6.3% (n = 2245), and 76% (n = 1701) of these underwent colonoscopy. The prevalence of findings were as follows: CRC, 4.8% (81/1701); advanced adenoma, 9.5% (162/1701); adenoma, 15.9% (270/1701); non-adenomatous polyps, 7.9% (135/1701); and no polyps or tumors, 25.4% (432/1701). Among participants aged 45-50 years, early onset-CRC had female predominance, while those ≥50 years with late onset-CRC were predominantly male. CRC was more prevalent in the left colon (P < 0.005). Conclusions: Approximately one-third of the participants diagnosed with CRC had early-onset CRC. Screening participation was desirable for the defined target population. Public education is necessary along with expanded colonoscopy resources to continue further citizen participation.

Indexed as

AdenomaColorectal NeoplasmsAgedColonoscopyEarly Detection of CancerFemaleHumansMaleMass ScreeningMiddle AgedSaudi ArabiaAdvanced adenomascolonoscopycolorectal cancer screeningearly onset

Identifiers

PMID36254929
PMCPMC10270470
OpenAlexW4306729895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.