Evidence map›Paper›PMID 36254901›Full record

SynthesisAnnals of cardiac anaesthesia

The use of cerebral oximetry in cardiac surgery: A systematic review and meta-analysis of randomized controlled trials.

Xin Hui Chiong, Zhen Zhe Wong, Siu Min Lim, Tyng Yan Ng, Ka Ting Ng

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of cardiac anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Review
  4. Comment on "Cerebral pulse oximetry in carotid endarterectomy: an impact study".Revista da Associacao Medica Brasileira (1992) · 2026
    Article
  5. Review
  6. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  7. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  8. Article
  9. Brain health: A concern for anaesthesiologists and intensivists.European journal of anaesthesiology and intensive care · 2024
    Review
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xin Hui ChiongSchool of Medicine, University of Aberdeen, United Kingdom.
Zhen Zhe WongSchool of Medicine, International Medical University, Kuala Lumpur, Malaysia.
Siu Min LimDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Tyng Yan NgDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Ka Ting NgDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
University of Malaya · MYInternational Medical University · MYUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High prevalence of cerebral desaturation is associated with postoperative neurological complications in cardiac surgery. However, the evidence use of cerebral oximetry by correcting cerebral desaturation in the reduction of postoperative complications remains uncertain in the literature. This systematic review and meta-analysis aimed to examine the effect of cerebral oximetry on the incidence of postoperative cognitive dysfunction in cardiac surgery. Databases of MEDLINE, EMBASE, and CENTRAL were searched from their inception until April 2021. All randomized controlled trials comparing cerebral oximetry and blinded/no cerebral oximetry in adult patients undergoing cardiac surgery were included. Observational studies, case series, and case reports were excluded. A total of 14 trials (n = 2,033) were included in this review. Our pooled data demonstrated that patients with cerebral oximetry were associated with a lower incidence of postoperative cognitive dysfunction than the control group (studies = 4, n = 609, odds ratio [OR]: 0.15, 95% confidence interval [CI]: 0.04 to 0.54, P = 0.003, I

Indexed as

Cardiac Surgical ProceduresDeliriumPostoperative Cognitive ComplicationsAdultHumansOximetryPostoperative ComplicationsRandomized Controlled Trials as TopicCardiac surgerycerebral oximetrycognitive dysfunctiondeliriumdesaturationmeta-analysis

Identifiers

PMID36254901
PMCPMC9732949
OpenAlexW4306730149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.