Evidence map›Paper›PMID 36254805›Full record

ArticleNeuropsychopharmacology reports2022

Development of individual fitness score for conformity of prescriptions to the "Guidelines For Pharmacological Therapy of Schizophrenia".

Ken Inada, Kentaro Fukumoto, Naomi Hasegawa, Yuka Yasuda, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Hitoshi Iida, Kazutaka Ohi, Hiroyuki Muraoka and 29 more

Open access · goldAbstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 20 institutions in 2 countries.

Ken InadaDepartment of Psychiatry, School of Medicine, Kitasato University, Sagamihara, Japan.ORCID 0000-0002-3073-4588
Kentaro FukumotoDepartment of Neuropsychiatry, Iwate Medical University, Iwate, Japan.
Naomi HasegawaDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Yuka YasudaDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Hisashi YamadaDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Hikaru HoriDepartment of Psychiatry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Kayo IchihashiDepartment of Neuropsychiatry, University of Tokyo Hospital, Tokyo, Japan.
Hitoshi IidaDepartment of Psychiatry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-2180-9998
Kazutaka OhiDepartment of Psychiatry, Gifu University Graduate School of Medicine, Gifu, Japan.ORCID 0000-0001-9577-9640
Hiroyuki MuraokaDepartment of Psychiatry, School of Medicine, Kitasato University, Sagamihara, Japan.
Fumitoshi KodakaDepartment of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan.
Kenta IdeDepartment of Hospital Pharmacy, Hospital of University of Occupational and Environmental Health, Fukuoka, Japan.
Naoki HashimotoDepartment of Psychiatry, Hokkaido University Graduate School of Medicine, Hokkaido, Japan.
Jun-Ichi IgaDepartment of Neuropsychiatry, Ehime University Graduate School of Medicine, Ehime, Japan.ORCID 0000-0003-4409-3096
Kazuyoshi OgasawaraCenter for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Achi, Japan.ORCID 0000-0003-2911-0708
Kiyokazu AtakeNippon Telegraph and Telephone West Corporation Kyushu Health Administration Center, Fukuoka, Japan.
Yoshikazu TakaesuDepartment of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.ORCID 0000-0002-9169-3249
Tatsuya NagasawaDepartment of NeuroPsychiatry Kanazawa Medical University, Ishikawa, Japan.
Hiroshi KomatsuDepartment of Psychiatry, Tohoku University Hospital, Miyagi, Japan.
Tsuyoshi OkadaDepartment of Psychiatry, Jichi Medical University, Tochigi, Japan.
Ryuji FurihataAgency for Student Support and Disability Resources, Kyoto University, Kyoto, Japan.
Mikio KidoKido Clinic, Toyama, Japan.
Saya KikuchiDepartment of Psychiatry, Tohoku University Hospital, Miyagi, Japan.
Chika KubotaDepartment of Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Manabu MakinodanDepartment of Psychiatry, Nara Medical University, Nara, Japan.
Shinichiro OchiDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Ehime, Japan.
Masahiro TakeshimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.ORCID 0000-0003-0614-7524
Hirotaka YamagataDivision of Neuropsychiatry, Department of Neuroscience Yamaguchi University School of Medicine, Yamaguchi, Japan.
Junya MatsumotoDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID 0000-0003-4228-3208
Kenichiro MiuraDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID 0000-0002-3722-7837
Masahide UsamiDepartment of Child and Adolescent Psychiatry, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, Japan.
Taishiro KishimotoHills Joint Research Laboratory for Future Preventive Medicine and Wellness, Keio University School of Medicine, Tokyo, Japan.
Toshiaki OnitsukaDepartment of Neuroimaging Psychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Eiichi KatsumotoKatsumoto Mental Clinic, Osaka, Japan.
Akitoyo HishimotoDepartment of Psychiatry, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
Shusuke NumataDepartment of Psychiatry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.
Norio Yasui-FurukoriDepartment of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0002-4414-3770
Koichiro WatanabeDepartment of Neuropsychiatry, School of Medicine, Kyorin University, Tokyo, Japan.
Ryota HashimotoDepartment of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID 0000-0002-5941-4238
National Center of Neurology and Psychiatry · JPFukuoka University · JPTohoku University Hospital · JPAkita University · JPDokkyo Medical University · JPEhime University · JPGifu University · JPHokkaido University · JPHyogo Medical University · JPIwate Medical University · JPJichi Medical University · JPJikei University School of Medicine · JPKanazawa Medical University · JPKeio University · JPKitasato University · JPKyorin University · JPKyoto University · JPKyushu University · JPMinamiaoyama Eye Clinic · JPNagoya University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which revealed a gap between the guidelines and actual clinical practice (evidence-practice-gap). The purpose of this study was to develop an individual fitness score (IFS) formula that expresses the degree to which prescribers adhere to the Guidelines for Pharmacological Therapy of Schizophrenia in a simple manner, and to determine the validity of this formula from a survey of the prescriptions of the EGUIDE project participants'.

methodsTo establish appropriate scores, members discussed the proposed formula and then voted on them. The IFS formula developed was set up so that antipsychotic monotherapy would be given 100 points, with points deducted if concomitant or adjunctive antipsychotic medications were used, and a minimum score of 0. To validate this formula, prescriptions of hospitalized schizophrenic patients at admission and at discharge were scored and compared.

resultIFS points vary and ranged from 0 to100. The average pre-admission score for all subjects was 45.6, and the average score at discharge was 54, those were significantly higher during discharge.

conclusionsWe developed an IFS formula, a tool to easily visualize the degree to which current prescriptions conform to the guidelines for the pharmacological treatment of schizophrenia.

Indexed as

Antipsychotic AgentsSchizophreniaHumansPrescriptionsAntipsychotic Agentsclinical practice guidelineindividual fitness score (IFS)prescriptionquality indicatorschizophrenia

Identifiers

PMID36254805
PMCPMC9773743
OpenAlexW4306691774

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.