Evidence map›Paper›PMID 36254249›Full record

ArticleClinical, cosmetic and investigational dermatology2022

The Pathogenic Mechanism of the

Peiyao Li, Jialin Qi, Baishun Zhou, Ting Ding, Juan Long, Heng Xiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Peiyao Li *Department of Pathology, School of Medicine, Hunan Normal University, Changsha, People's Republic of China.
Jialin Qi *Department of Pathology, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Baishun ZhouDepartment of Pathology, School of Medicine, Hunan Normal University, Changsha, People's Republic of China.
Ting DingDepartment of Endocrinology, Yiyang Central Hospital, Yiyang, People's Republic of China.
Juan LongDepartment of Dermatology, Hunan Children's Hospital, Changsha, People's Republic of China.
Heng XiaoDepartment of Pathology, School of Medicine, Hunan Normal University, Changsha, People's Republic of China.ORCID 0000-0002-4765-2597
Hunan Normal University · CNCentral South University · CNHunan Children's Hospital · CNMinistry of Education of the People's Republic of China · CNYantai Laiyang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hailey-Hailey disease (HHD) is an autosomal dominant cutaneous disorder that manifests as repeated blisters and erosions on flexural or intertriginous skin areas. The calcium-transporting ATPase type 2C member 1 gene ( Methods: In this study, the identified Results: Cycloheximide chase assay showed that the degradation rate of the SPCA1 mutant was not obviously faster than that of the normal SPCA1. CCK8 assay showed that cell proliferation rates in the wild-type, A109_Q120del, and empty vector control groups all decreased in the gradient Mn Conclusion: These results demonstrate that the

Indexed as

ATPase secretory pathway Ca2+ transporting 1Hailey–Hailey diseasepathogenesissecretory pathway Ca2+/Mn2+-ATPase 1

Identifiers

PMID36254249
PMCPMC9569160
OpenAlexW4304118884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.