ArticlePhotoacoustics2022
Freehand scanning photoacoustic microscopy with simultaneous localization and mapping.
Article in Photoacoustics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Linking Adjuvant Immune Stimulation to Spatiotemporal Dynamics via Cross-Scale Photoacoustic Microscopy.Chemical & biomedical imaging · 2026Article
- Robust hybrid feature-driven on-the-fly mapping enables freehand 3D panoramic photoacoustic angiography.Light, science & applications · 2026Article
- A handheld photoacoustic microscopic probe integrating a transparent ultrasound transducer and a fiber scanner.Nature communications · 2025Article
- Ring-segment piezopolymer sensor optimized for cylindrical-wave detection in optical-resolution optoacoustic angiography with extended imaging depth.Biomedical optics express · 2025Article
- Sparse scanning encoding and neural network decoding for compressed photoacoustic microscopy.Photoacoustics · 2025Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- Quantitative volumetric photoacoustic assessment of vasoconstriction by topical corticosteroid application in mice skin.Photoacoustics · 2024Article
- Unsupervised deep learning enables real-time image registration of fast-scanning optical-resolution photoacoustic microscopy.Photoacoustics · 2024Article
- Perspectives on endoscopic functional photoacoustic microscopy.Applied physics letters · 2024Article
- Free-moving-state microscopic imaging of cerebral oxygenation and hemodynamics with a photoacoustic fiberscope.Light, science & applications · 2024Article
- Review of low-cost light sources and miniaturized designs in photoacoustic microscopy.Journal of biomedical optics · 2024Review
- Photoacoustic imaging plus X: a review.Journal of biomedical optics · 2024Review
- High speed innovations in photoacoustic microscopy.Npj imaging · 2024Review
- Review of Three-Dimensional Handheld Photoacoustic and Ultrasound Imaging Systems and Their Applications.Sensors (Basel, Switzerland) · 2023Review
- Editorial: Breaking the speed limits in photoacoustic microscopy.Photoacoustics · 2023Article
- Simultaneous dual-modal photoacoustic and harmonic ultrasound microscopy with an optimized acoustic combiner.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical-resolution photoacoustic microscopy offers high-resolution, label-free hemodynamic and functional imaging to many biomedical applications. However, long-standing technical barriers, such as limited field of view, bulky scanning probes, and slow imaging speed, have limited the application of optical-resolution photoacoustic microscopy. Here, we present freehand scanning photoacoustic microscopy (FS-PAM) that can flexibly image various anatomical sites. We develop a compact handheld photoacoustic probe to acquire 3D images with high speed, and great flexibility. The high scanning speed not only enables video camera mode imaging but also allows for the first implementation of simultaneous localization and mapping (SLAM) in photoacoustic microscopy. We demonstrate fast in vivo imaging of some mouse organs, and human oral mucosa. The high imaging speed greatly reduces motion artifacts and distortions from tissue moving, breathing, and unintended handshaking. We demonstrate small-lesion localization in a large region of the brain. FS-PAM offers a flexible high-speed imaging tool with an extendable field of view, enabling more biomedical imaging applications.
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