Evidence map›Paper›PMID 36254232›Full record

ArticleOxidative medicine and cellular longevity2022

Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.

Eryi Sun, Jing Zhang, Yan Deng, Jun Wang, Qi Wu, Wei Chen, Xiaodong Ma, Siyuan Chen, Xin Xiang, Yujie Chen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Eryi SunDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0002-6772-1246
Jing ZhangDepartment of Nursing, The 904th Hospital of PLA, Medical School of Anhui Medical University, Wuxi 214044, China.
Yan DengWest China Hospital of Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-1179-9896
Jun WangDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0002-5514-4808
Qi WuDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0002-0957-5957
Wei ChenDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.
Xiaodong MaDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.
Siyuan ChenDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.
Xin XiangDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.ORCID https://orcid.org/0000-0003-1695-9534
Yujie ChenDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.ORCID https://orcid.org/0000-0002-9905-9138
Tairong WuDepartment of Traditional Chinese Medicine, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0002-5571-9122
Yang YangDepartment of Nursing, The 904th Hospital of PLA, Medical School of Anhui Medical University, Wuxi 214044, China.ORCID https://orcid.org/0000-0001-6472-5578
Bo ChenDepartment of Neurosurgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0003-1756-5000
Jiangsu University · CNArmy Medical University · CNAnhui Medical University · CNGuiyang Medical University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitophagy, the selective removal of damaged mitochondria through autophagy, is crucial for mitochondrial turnover and quality control. Docosahexaenoic acid (DHA), an essential omega-3 fatty acid, protects mitochondria in various diseases. This study aimed to investigate the neuroprotective role of DHA in ischaemic stroke models

Indexed as

Brain InjuriesBrain IschemiaIschemic StrokeNeuroprotective AgentsStrokeAdenosine TriphosphateAnimalsBrainDocosahexaenoic AcidsDynaminsGlucoseGlutamatesMiceMitophagyOxygenProtein KinasesAdenosine TriphosphateDocosahexaenoic AcidsDynaminsGlucoseGlutamatesNeuroprotective AgentsOxygenProtein KinasesReactive Oxygen SpeciesSuccinatesUbiquitin-Protein Ligases

Identifiers

PMID36254232
PMCPMC9569200
OpenAlexW4303832801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.