Evidence map›Paper›PMID 36254196›Full record

ArticleClinical & translational immunology2022

Parallel detection of SARS-CoV-2 epitopes reveals dynamic immunodominance profiles of CD8

Jet van den Dijssel, Ruth R Hagen, Rivka de Jongh, Maurice Steenhuis, Theo Rispens, Dionne M Geerdes, Juk Yee Mok, Angela Hm Kragten, Mariël C Duurland, Niels Jm Verstegen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. The ageing immune system and its battle with viruses.The Journal of general virology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Jet van den DijsselDepartment of Hematopoiesis Sanquin Research Amsterdam The Netherlands.
Ruth R HagenDepartment of Hematopoiesis Sanquin Research Amsterdam The Netherlands.
Rivka de JonghLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Maurice SteenhuisLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Theo RispensLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Dionne M GeerdesSanquin Reagents B.V. Amsterdam The Netherlands.
Juk Yee MokSanquin Reagents B.V. Amsterdam The Netherlands.
Angela Hm KragtenSanquin Reagents B.V. Amsterdam The Netherlands.
Mariël C DuurlandLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Niels Jm VerstegenLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
S Marieke van HamLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Wim Je van EschSanquin Reagents B.V. Amsterdam The Netherlands.
Klaas Pjm van GisbergenDepartment of Hematopoiesis Sanquin Research Amsterdam The Netherlands.
Pleun HombrinkDepartment of Hematopoiesis Sanquin Research Amsterdam The Netherlands.
Anja Ten BrinkeLandsteiner Laboratory Amsterdam UMC location University of Amsterdam Amsterdam The Netherlands.
Carolien E van de SandtDepartment of Hematopoiesis Sanquin Research Amsterdam The Netherlands.ORCID https://orcid.org/0000-0002-4155-7433
Sanquin · NLThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: High-magnitude CD8 Methods: CD8 Results: A comprehensive panel of 49 mostly conserved SARS-CoV-2-specific CD8 Conclusion: SARS-CoV-2 infection induces a predominant CD8

Indexed as

CD8+ T cellsconvalescenceepitopesimmunodominanceinfectionSARS‐CoV‐2

Identifiers

PMID36254196
PMCPMC9568370
OpenAlexW4306734479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.