Evidence map›Paper›PMID 36254188›Full record

ArticlePsychiatric research and clinical practice2022

Trajectories of Depressive and Anxiety Symptoms Across Pregnancy and Postpartum in Selective Serotonin Reuptake Inhibitor-Treated Women.

Gabrielle A Mesches, Jody D Ciolino, Catherine S Stika, Dorothy K Sit, Katelyn Zumpf, Sheehan Fisher, Crystal T Clark, Alfred L George, Michael J Avram, Laura J Rasmussen-Torvik and 10 more

Open access · goldAbstract read
In one paragraph

Article in Psychiatric research and clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Prenatal serotonin reuptake inhibitor exposure and maternal depression symptoms are associated with altered fetal brain and placental development.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Observational
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Gabrielle A MeschesDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Jody D CiolinoDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Catherine S StikaDepartment of Obstetrics and Gynecology Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Dorothy K SitDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Katelyn ZumpfDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Sheehan FisherDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Crystal T ClarkDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Alfred L GeorgeDepartment of Pharmacology Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Michael J AvramDepartment of Anesthesiology Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Laura J Rasmussen-TorvikDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Daniel L EricksonDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Steven CaritisDepartment of Obstetrics, Gynecology, and Reproductive Sciences University of Pittsburgh Magee Womens Hospital Pittsburgh Pennsylvania USA.
Dawn FischerDepartment of Obstetrics, Gynecology, and Reproductive Sciences University of Pittsburgh Magee Womens Hospital Pittsburgh Pennsylvania USA.
Raman VenkataramananDepartment of Pharmaceutical Sciences University of Pittsburgh School of Pharmacy Pittsburgh Pennsylvania USA.
Maged CostantineDepartment of Maternal-Fetal Medicine The Ohio State University Wexner Medical Center Columbus Ohio USA.
Holly WestDepartment of OB/GYN University of Texas Medical Branch Galveston Texas USA.
Elizabeth WelchDepartment of OB/GYN University of Texas Medical Branch Galveston Texas USA.
Shannon ClarkDepartment of OB/GYN University of Texas Medical Branch Galveston Texas USA.
Katherine L WisnerDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.
Jacqueline K GollanDepartment of Psychiatry and Behavioral Sciences Northwestern University Feinberg School of Medicine Chicago Illinois USA.ORCID https://orcid.org/0000-0003-2315-4347
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
Plasma SSRI Concentrations and CYP450 Activity Across ChildbearingU54HD085601 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GEORGE, ALFRED L., STIKA, CATHERINE S. · 2015 to 2019
$3.9M
NCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1 TR001439NICHD NIH HHS U54 HD085601
6 · The paper itself

Abstract

Objective: Tracking perinatal mood and anxiety disorders is championed by the American Psychiatric Association and the International Marcé Society for Perinatal Mental Health. We conducted this study to examine trajectories of monthly depressive and anxiety symptoms through pregnancy and postpartum. Methods: This is a prospective longitudinal observational cohort study of pregnant women interviewed at baseline (≤18th gestational week), every four weeks through delivery and at 6 and 14 weeks postpartum at three urban academic medical centers ( Results: Three relatively stable depression trajectories emerged, described as Minimal, Mild, and Subthreshold, in each group across pregnancy. Two of the four anxiety trajectories were stable, including Asymptomatic and Minimal, while the third, termed Breakthrough, was ascending with increasing symptoms and the fourth trajectory, described as Mild, had descending symptoms. Conclusions: Screening for anxiety with depression for pregnant women will yield a comprehensive view of psychiatric symptoms and treatment targets in perinatal women.

Identifiers

PMID36254188
PMCPMC9558923
OpenAlexW4214874635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.