Evidence map›Paper›PMID 36254163›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2022

Disability Retirement After First Admission with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Danish Nationwide Registry Cohort Study Using a Retrospective Follow-Up Design.

Peter Ascanius Jacobsen, Kristian Kragholm, Christian Torp-Pedersen, Ulla Møller Weinreich

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Peter Ascanius JacobsenDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0001-6083-7441
Kristian KragholmThe Clinical Institute, Aalborg University, Aalborg, Denmark.ORCID 0000-0001-9629-8670
Christian Torp-PedersenDepartment of Clinical Research, Hillerød Hospital, Hillerød, Denmark.ORCID 0000-0003-2892-6131
Ulla Møller WeinreichDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0003-1975-3654
Aalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Many chronic obstructive pulmonary disease (COPD) patients below retirement age are outside the workforce. The existing knowledge about association between acute exacerbation of COPD (AECOPD) and disability retirement is limited. Aim: The aim of this study is to explore disability retirement in COPD patients 3 years following first-ever AECOPD. Methods: This retrospective registry-based follow-up cohort study design is based on nationwide Danish registry data. Patients admitted to the hospital for the first time between 1999 and 2017 with AECOPD and age between 35 and 59 years, active in the workforce, were included in the study. Socio-demographics, comorbidities and inhaled medication use were explored. COPD patients' hazard ratio of disability retirement during 3-year follow-up was calculated. Cox regression was used to examine the effects of covariates on disability retirement. Results: A total of 4032 patients were included in the study. During follow-up, 17.2% (692/4032) experienced disability retirement from the workforce. Factors associated with disability retirement were expressed as hazard ratio (95% confidence intervals): Higher age (ref. age 46-50: Age 51-55, 1.42, (1.12-1.81); age 56-59, 1.37 (1.08-1.74)); living alone (1.34 (1.14-1.56)); number of comorbidities for 1, 2, and 3 comorbidities (1.36 (1.14-1.62), 1.57 (1.19-2.07), 1.77 (1.20-2.60)); emphysema (2.01 (1.44-2.79)); depression (1.60 (1.12-2.28)); cardiac comorbidity (1.38 (1.07-1.78)); triple inhalation therapy (2.76 (2.20-3.47)); ICS + LAMA or ICS + LABA treatment (1.82 (1.48-2.23)); and ICS treatment (1.49 (1.17-1.90)). Higher educational level was associated with a significantly reduced risk of disability retirement, medium, short higher and long higher educational level, relative to low education level (0.78 (0.67-0.91), 0.63 (0.48-0.83) and 0.27 (0.12-0.60)). Conclusion: Patients vulnerable to disability retirement are patients with markers of severe COPD, comorbidities, and social vulnerability.

Indexed as

Pulmonary Disease, Chronic ObstructiveAdministration, InhalationAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAdultCohort StudiesDenmarkDrug Therapy, CombinationFollow-Up StudiesHumansMiddle AgedMuscarinic AntagonistsRegistriesRetirementRetrospective StudiesAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsMuscarinic Antagonistschronic obstructive pulmonary diseasecomorbiditiesearly retirementreturn to work

Identifiers

PMID36254163
PMCPMC9569162
OpenAlexW4303985935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.