Evidence map›Paper›PMID 36254142›Full record

ArticleCase reports in cardiology2022

Achalasia as an Unusual Cause of Acute Cellular Rejection of a Transplanted Heart.

Amanda Fernandes, Crystal Lihong Yan, Phillip Ruiz, Nina Thakkar Rivera

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amanda FernandesDivision of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL, USA.ORCID https://orcid.org/0000-0002-7443-5029
Crystal Lihong YanDivision of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL, USA.ORCID https://orcid.org/0000-0003-1724-4231
Phillip RuizDepartments of Surgery and Pathology, University of Miami/Jackson Memorial Hospital, Miami, FL, USA.ORCID https://orcid.org/0000-0003-2291-4594
Nina Thakkar RiveraDivision of Cardiology, Miami Transplant Institute, University of Miami/Jackson Memorial Hospital, Miami, FL, USA.ORCID https://orcid.org/0000-0002-6843-162X
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 68-year-old female with end-stage heart failure presented to the hospital for heart transplant. She was diagnosed with achalasia 14 months prior and treated with frequent botulinum toxin injections. She underwent orthotopic heart transplant on the day of admission and was extubated a few days later. She developed intractable nausea and vomiting. Her first endomyocardial biopsy revealed moderate, approaching severe rejection. She was treated with high-dose intravenous pulse steroids. Fluoroscopy at the time of follow-up biopsy showed undigested pills in her esophagus with narrowing at the distal end and thus failure to deliver immunosuppressive therapy. This case highlights achalasia as an etiology for acute rejection and its potential management.

Identifiers

PMID36254142
PMCPMC9569230
OpenAlexW4297521541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.