Evidence map›Paper›PMID 36254133›Full record

ArticlePrzeglad menopauzalny = Menopause review2022

The effect of transcranial photobiomodulation on cognitive function and attentional performance of older women with mild cognitive impairment: a randomized controlled trial.

Shahab Papi, Hamid Allahverdipour, Ali Jahan, Iman Dianat, Mohammad Asghari Jafarabadi, Maryam Moghadam Salimi

Registry-linked trialAbstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06618807 (A Pilot Study Evaluating the Feasibility, Safety, and Efficacy of the Neuro RX Gamma), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06618807 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study Evaluating the Feasibility, Safety, and Efficacy of the Neuro RX Gamma (Version 2) for the Treatment of Mild Cognitive Impairment (MCI)

TypeinterventionalSponsorUnity Health TorontoRan2025 to 2028Enrolled60ConditionsMild Cognitive Impairment (MCI) Due to Alzheimer's DiseaseArmsActive tPBM device, Sham device
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahab PapiDepartment of Public Health, School of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Hamid AllahverdipourDepartment of Health Education and Promotion, Faculty of Health Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Ali JahanDepartment of Speech Therapy, Faculty of Rehabilitation Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Iman DianatDepartment of Occupational Health and Ergonomics, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Asghari JafarabadiDepartment of Statistic and Epidemiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam Moghadam SalimiDepartment of Physical Therapy, Faculty of Rehabilitation Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mild cognitive impairment (MCI) is a progressive age-related condition caused by physiological and structural changes in the brain, such as neurodegeneration and hypometabolism. Transcranial photobiomodulation (tPBM) is a neuromodulation technique that improves brain metabolism and oxygenation by irradiating red to near-infrared light on a specific area of the head. This study aimed to investigate the effect of multi-session tPBM on the cognitive capacities and attentional function of older women with MCI. Material and methods: In this randomized controlled trial, 42 older women with MCI were randomly assigned to 2 equal groups: real and sham. The mini-mental state examination (MMSE) and the attentional Go/No-Go task were used to examine the patients. On the right frontal-pole of the cortex, 5 sessions of 850 nm tPBM were given. Re-examinations were conducted on the participants. For the Go/No-Go task, the reaction time to the target (RTT), the percentage of correct trials (PCT), and the efficiency score (ES) were measured. Results: The findings revealed a significant interaction between group × time for MMSE ( Conclusions: According to the findings of this study, tPBM had a positive effect on older people's attention and cognitive abilities.

Indexed as

mild cognitive impairmentolder adultssustained attentiontranscranial photobiomodulationwomen

Identifiers

PMID36254133
PMCPMC9551363

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.