ArticlePrzeglad menopauzalny = Menopause review2022
The accuracy of the calcium-creatinine ratio in a spot urine sample for predicting preeclampsia.
Article in Przeglad menopauzalny = Menopause review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Understanding Renal Tubular Function: Key Mechanisms, Clinical Relevance, and Comprehensive Urine Assessment.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Review
- The relation between serum uric acid and severity of preeclampsia in pregnant women: a cross-sectional study.Przeglad menopauzalny = Menopause review · 2023Article
- Maternal and fetal outcomes after bariatric surgeries.Przeglad menopauzalny = Menopause review · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Preeclampsia (PE) is a major cause of foetal and maternal morbidity. Currently, there is no reliable diagnostic test to predict PE.To evaluate the accuracy of the calcium-creatinine ratio (CCR) in a spot urine sample for the prediction of PE. Material and methods: Two hundred and forty-six pregnant women, attending the ante-natal clinic after 20 weeks` gestation were included in this study. After exclusion of pre-existing chronic renal disease affecting calcium and/or creatinine excretion, spot urine samples were taken from participants to detect the CCR. Participants were followed up until delivery; the women who developed PE were included in the PE group and compared with normotensive controls to evaluate the accuracy of CCR in a spot urine sample for the prediction of PE. Results: The gestational age at delivery and parity were significantly lower in the studied PE group compared to normotensive controls (36.1 ±4.3 weeks and 1.7 ±2.6 vs. 39.1 ±3.1 and 3.4 ±1.9; respectively), ( Conclusions: The calcium-creatinine ratio ≤ 0.04 had 79.3% sensitivity, 96.3% specificity, 91.5% PPV, 90.3% NPV, and 90.7% overall accuracy in predicting PE. This study suggests the use of CCR in spot urine sample for screening and early detection of PE.
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Registered trials
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