Evidence map›Paper›PMID 36254106›Full record

ReviewEuropean journal of clinical investigation2023

Big data and machine learning to tackle diabetes management.

Ana F Pina, Maria João Meneses, Inês Sousa-Lima, Roberto Henriques, João F Raposo, Maria Paula Macedo

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of clinical investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Predictive voting model for early diagnosis of diabetes dataset.Frontiers in cardiovascular medicine · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Artificial intelligence in pediatric allergy research.European journal of pediatrics · 2024
    Review
  8. Review
  9. Article
  10. Review
  11. Machine learning prediction of mortality in Acute Myocardial Infarction.BMC medical informatics and decision making · 2023
    Article
  12. Article
  13. Big data and machine learning to tackle diabetes management.European journal of clinical investigation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ana F PinaiNOVA4Health, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0001-8135-7420
Maria João MenesesiNOVA4Health, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-8236-5411
Inês Sousa-LimaiNOVA4Health, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-1859-0486
Roberto HenriquesNOVA Information Management School (NOVA IMS), Universidade NOVA de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-4862-8177
João F RaposoiNOVA4Health, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-2589-7208
Maria Paula MacedoiNOVA4Health, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-2549-0275
Associacao Protectora dos Diabeticos de Portugal · PTUniversidade Nova de Lisboa · PT

Funding

European Commission Marie Skłodowska-Curie Action H2020 734719FEDER ALT20-03-0247-FEDER-113469FEDER LISBOA-01-0247-FEDER-113469Fundação para a Ciência e a Tecnologia PD/BD/136887/2018Fundação para a Ciência e a Tecnologia PTDC/BIM-MET/2115/2014Fundação para a Ciência e a Tecnologia PTDC/MEC-MET/29314/2017Fundação para a Ciência e a Tecnologia UIDB/Multi/04462/2020Sociedade Portuguesa de Diabetologia
6 · The paper itself

Abstract

backgroundType 2 Diabetes (T2D) diagnosis is based solely on glycaemia, even though it is an endpoint of numerous dysmetabolic pathways. Type 2 Diabetes complexity is challenging in a real-world scenario; thus, dissecting T2D heterogeneity is a priority. Cluster analysis, which identifies natural clusters within multidimensional data based on similarity measures, poses a promising tool to unravel Diabetes complexity.

methodsIn this review, we scrutinize and integrate the results obtained in most of the works up to date on cluster analysis and T2D.

resultsTo correctly stratify subjects and to differentiate and individualize a preventive or therapeutic approach to Diabetes management, cluster analysis should be informed with more parameters than the traditional ones, such as etiological factors, pathophysiological mechanisms, other dysmetabolic co-morbidities, and biochemical factors, that is the millieu. Ultimately, the above-mentioned factors may impact on Diabetes and its complications. Lastly, we propose another theoretical model, which we named the Integrative Model. We differentiate three types of components: etiological factors, mechanisms and millieu. Each component encompasses several factors to be projected in separate 2D planes allowing an holistic interpretation of the individual pathology.

conclusionFully profiling the individuals, considering genomic and environmental factors, and exposure time, will allow the drive to precision medicine and prevention of complications.

Indexed as

Big DataDiabetes Mellitus, Type 2Cluster AnalysisHumansMachine LearningPrecision Medicinebig datacluster analysisdiabetesmachine learning

Identifiers

PMID36254106
PMCPMC10078354
OpenAlexW4306673865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.