Evidence map›Paper›PMID 36253837›Full record

ArticleParasites & vectors2022

Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil.

Vamilton Alvares Santarém, Anahi Chechia do Couto, Susana Zevallos Lescano, William Henry Roldán, Ruana Renostro Delai, Rogério Giuffrida, Louise Bach Kmetiuk, Alexander Welker Biondo, Sriveny Dangoudoubiyam, Andrea Pires Dos Santos

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Vamilton Alvares SantarémGraduate College in Animal Sciences, University of Western São Paulo (UNOESTE), Presidente Prudente, SP, 19050-920, Brazil.
Anahi Chechia do CoutoGraduate College of Cellular and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, PR, 81531-970, Brazil.
Susana Zevallos LescanoInstitute of Tropical Medicine of São Paulo, University of São Paulo, Butantã, SP, 05403-000, Brazil.
William Henry RoldánInstitute of Tropical Medicine of São Paulo, University of São Paulo, Butantã, SP, 05403-000, Brazil.
Ruana Renostro DelaiDepartment of Veterinary Medicine, Federal University of Paraná (UFPR), Curitiba, PR, 80035-050, Brazil.
Rogério GiuffridaDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Louise Bach KmetiukDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Alexander Welker BiondoGraduate College of Cellular and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, PR, 81531-970, Brazil. abiondo@ufpr.br.
Sriveny DangoudoubiyamDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Andrea Pires Dos SantosDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Purdue University West Lafayette · USUniversidade Federal do Paraná · BRInstituto Butantan · BRUniversidade do Oeste Paulista · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite being one of the most prevalent helminth parasitic zoonoses worldwide and particularly in socioeconomically vulnerable populations, toxocariasis remains to be fully investigated in persons experiencing homelessness. Accordingly, the present study has aimed to assess the seroprevalence and associated risk factors of Toxocara spp. exposure in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo city, Brazil.

methodsAnti-Toxocara IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA). Univariable and multivariable logistic regression models were performed to assess the risks for toxocariasis.

resultsOverall, anti-Toxocara IgG antibodies were detected in 89/194 (45.9%, 95% CI: 39.0-52.9%) persons experiencing homelessness, twice as high (OR = 2.2; 95% CI = 1.245-3.873; P = 0.0089) than the frequency of 22/79 (27.8%, 95% CI: 19.2-38.6) in shelter workers. College education was the only protective factor for Toxocara spp. exposure (OR: 0.23; P = 0.018) revealed by logistic regression.

conclusionsAlthough indicating a multifactorial origin of toxocariasis, the present study has assessed a highly vulnerable population with high disease risks and premature death. Thus, the living conditions of the homeless population have influenced the high prevalence of anti-Toxocara antibodies verified here compared with domiciled shelter workers. Despite being less exposed, shelter and other outdoor workers may present an occupational risk to toxocariasis. Future studies should establish whether such environmental exposure might occur in persons experiencing homelessness in other regions worldwide.

Indexed as

Ill-Housed PersonsToxocariasisAnimalsAntibodies, HelminthBrazilEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin GRisk FactorsSeroepidemiologic StudiesToxocaraAntibodies, HelminthImmunoglobulin GHomelessSeroprevalenceToxocariasisZoonosis

Identifiers

PMID36253837
PMCPMC9574839
OpenAlexW4306405597

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.