Evidence map›Paper›PMID 36253824›Full record

ReviewWorld journal of surgical oncology2022

Literature review of imaging, pathological diagnosis, and outcomes of metachronous lung and pancreatic metastasis of cecal cancer.

Xiang Wu, Shuping Zhou, Xinhua Zhou, Xiao Xu, Luoluo Wang, Yi Ruan, Jun Lu, Haili Li, Hongfeng Xu, Xinyi Ma and 1 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Xiang Wu *Department of Hepatobiliary and Pancreatic Surgery, Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo, 315000, China.
Shuping Zhou *Ningbo Municipal Health Vocational and Technical College, Ningbo, 315100, China.
Xinhua ZhouDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo, 315000, China. zhouxinhua1002@163.com.
Xiao XuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Luoluo WangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo, 315000, China.
Yi RuanDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo, 315000, China.
Jun LuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Haili LiDepartment of Diagnosis, Ningbo Diagnostic Pathology Center, Ningbo, 315000, China.
Hongfeng XuDepartment of General Surgery, The Third People's Hospital Health Care Group of Cixi, Ningbo, 315300, China.
Xinyi MaDepartment of Pathology, Hangzhou DIAN Medical Laboratory, Hangzhou, 310000, China.
Hong LiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Li Huili Hospital, Ningbo University School of Medicine, Ningbo, 315000, China. lancet2017@163.com.
Ningbo University · CNDian Diagnostics (China) · CNHangzhou First People's Hospital · CNNingbo College of Health Sciences · CNZhejiang University · CN

Funding

Ningbo Digestive System Cancer Clinical Medicine Research Center (2019A21003) 2019A21003
6 · The paper itself

Abstract

backgroundPancreatic metastasis from colorectal cancer is extremely rare. Here, we report a case of colorectal cancer with lung and pancreatic metastasis and analyze the histopathology, immunohistochemistry, and next-generation sequencing (NGS) to generate a differential diagnosis and treatment of metastatic colon cancer. CASE PRESENTATION: AC1 A 78-year-old man was admitted because of a recently elevated carcinoembryonic antigen. This patient had undergone laparoscopic right hemicolectomy for cecal cancer IIA (T3N0M0) 5 years before admission, and thoracoscopic left upper lung wedge resection for primary colon cancer lung metastasis 2 years before admission. At that time, the patient was thought to have pancreatic metastasis from colon cancer. He underwent laparoscopic distal pancreatectomy (combined with splenectomy). Postoperative pathology revealed colon cancer metastasis. We performed NGS on tumor samples at three loci and found colon cancer's most common oncogenic driver genes (KRAS, APC, and TP53). One month after surgery, the patient was given capecitabine for six cycles of chemotherapy. At present, no high adverse reactions have been reported. DISCUSSION: For patients with pancreatic space-occupying, such as a previous history of colorectal cancer, and recent carcinoembryonic antigen elevation, we should highly suspect pancreatic metastatic colorectal cancer. NGS is an essential auxiliary for identifying metastatic tumors. Surgery combined with postoperative chemotherapy is an effective treatment.

Indexed as

Cecal NeoplasmsColonic NeoplasmsPancreatic NeoplasmsRectal NeoplasmsAgedCapecitabineCarcinoembryonic AntigenHumansLungMaleProto-Oncogene Proteins p21(ras)CapecitabineCarcinoembryonic AntigenProto-Oncogene Proteins p21(ras)Colon cancerImmunohistochemistryLung metastasesNGSPancreatic metastasesTreatment

Identifiers

PMID36253824
PMCPMC9575218
OpenAlexW4306399293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.