SynthesisWorld journal of surgical oncology2022
ME-NBI combined with endoscopic ultrasonography for diagnosing and staging the invasion depth of early esophageal cancer: a diagnostic meta-analysis.
Synthesis in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Usefulness of 18F-fluorodeoxyglucose positron emission tomography for T1 esophageal squamous cell carcinoma.Medicine · 2026Article
- Early cardia neoplasms in the upper gastrointestinal tract have a higher detection rate under sedation: a retrospective cohort study based on the Chinese population.Frontiers in medicine · 2026Article
- Location characteristics of superficial esophageal squamous cell carcinoma.Scientific reports · 2025Article
- Endoscopic Ultrasound in Squamous Cell Esophageal Cancer: From Staging to Strategy-A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- RegGAN-based contrast-free CT enhances esophageal cancer assessment: multicenter validation of automated tumor segmentation and T-staging.La Radiologia medica · 2025Article
- Artificial intelligence enhances the management of esophageal squamous cell carcinoma in the precision oncology era.World journal of gastroenterology · 2024Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSeveral methods can assist in detecting early esophageal cancer (EEC) and staging esophageal cancer (EC) invasion depth.
objectiveTo evaluate the accuracy of magnifying endoscopy with narrow-band imaging (ME-NBI) plus endoscopic ultrasonography (EUS) for diagnosing EC.
methodsWe searched the PubMed, Embase, Cochrane Library, and China National Knowledge Infrastructure (CNKI) databases for relevant studies. The Quality Assessment of Diagnostic Accuracy Studies 2 (QADAS2) was used to assess the studies' methodological quality. The sensitivity, specificity, positive likelihood (LR+), negative likelihood (LR-), and diagnostic odds ratio (DOR) were calculated, and the summary receiver operating characteristic (SROC) curves were drawn to evaluate the diagnostic performance.
resultsSeven studies were included. The meta-analysis suggested that the pooled sensitivity, specificity, LR+, LR-, and DOR of ME-NBI plus EUS for diagnosing EC were 0.947 (95% confidence interval [CI], 0.901-0.975), 0.894 (95% CI, 0.847-0.931), 7.989 (95% CI, 4.264-14.970), 0.066 (95% CI, 0.035-0.124), and 137.96 (95% CI, 60.369-315.27), respectively. Those values for staging the invasive depth were 0.791 (95% CI, 0.674-0.881), 0.943 (95% CI, 0.906-0.968), 13.087 (95% CI, 7.559-22.657), 0.226 (95% CI, 0.142-0.360), and 61.332 (95% CI, 27.343-137.57). The areas under the curves (AUCs) for diagnosis and staging were 0.97 and 0.95, respectively.
conclusionsME-NBI plus EUS might be an adequate diagnostic and staging modality for EC. Due to the study limitations, more large-scale, high-quality studies are needed to confirm the diagnostic accuracy of ME-NBI plus EUS.
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