Evidence map›Paper›PMID 36253663›Full record

Trial reportMolecular imaging and biology2023

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Elizabeth J de Koster, Adriana C H van Engen-van Grunsven, Johan Bussink, Cathelijne Frielink, Lioe-Fee de Geus-Oei, Benno Kusters, Hans Peters, Wim J G Oyen, Dennis Vriens, EFFECTS trial study group

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Molecular imaging and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02208544 (Efficacy of [18F]-2-fluoro-2-deoxy-D-glucose Positron Emission Tomography), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02208544 nacompletednot on this map

Efficacy of [18F]-2-fluoro-2-deoxy-D-glucose Positron Emission Tomography (FDG-PET) in Evaluation of Cytological Indeterminate Thyroid Nodules Prior to Surgery: a Multicentre Cost-effectiveness Study

TypeinterventionalSponsorRadboud University Medical CenterRan2015 to 2022Enrolled132ConditionsThyroid Nodule, Thyroid NeoplasmsArmsDiagnostic Thyroid Surgery, Ultrasound of the head and neck, FDG-PET/CT
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Molecular Diagnostics and [Thyroid : official journal of the American Thyroid Association · 2024
    Trial
  2. Article
  3. Review
  4. Molecular Insights into BZW1 Expression and [Molecular imaging and biology · 2026
    Article
  5. [Future oncology (London, England) · 2025
    Article
  6. Article
  7. Article
  8. Endocrinology application of molecular imaging: current role of PET/CT.Journal of endocrinological investigation · 2024
    Review
  9. Preoperative stratification of cytologically indeterminate thyroid nodules by [European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Elizabeth J de KosterDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands. Lisanne.deKoster@radboudumc.nl.ORCID http://orcid.org/0000-0001-8111-1172
Adriana C H van Engen-van GrunsvenDepartment of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0002-3154-3601
Johan BussinkDepartment of Radiation Oncology, Radiotherapy & OncoImmunology Laboratory, Radboud University Medical Center, Nijmegen, Netherlands.ORCID http://orcid.org/0000-0002-5751-4796
Cathelijne FrielinkDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.
Lioe-Fee de Geus-OeiDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0003-1817-2743
Benno KustersDepartment of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Hans PetersDepartment of Radiation Oncology, Radiotherapy & OncoImmunology Laboratory, Radboud University Medical Center, Nijmegen, Netherlands.ORCID http://orcid.org/0000-0003-4353-8970
Wim J G OyenDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0001-8235-7078
Dennis VriensDepartment of Radiology, Section of Nuclear Medicine, Leiden University Medical Center, Leiden, the Netherlands.ORCID http://orcid.org/0000-0001-5762-6766
EFFECTS trial study group
Radboud University Nijmegen · NLHumanitas University · ITLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe current study explored the association between 2-[ PROCEDURES: Using a case-control design, 24 patients were selected from participants of a randomized controlled multicenter trial (NCT02208544) in which [

resultsThe expression of GLUT1, GLUT3, HK2, and MCT4 was strongly positively correlated with the SUV

conclusionsOur results suggest that [

Indexed as

Thyroid NeoplasmsThyroid NoduleFluorodeoxyglucose F18Glucose Transporter Type 1GlycolysisHumansHypoxiaPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsVascular Endothelial Growth Factor AFluorodeoxyglucose F18Glucose Transporter Type 1RadiopharmaceuticalsVascular Endothelial Growth Factor A[18F]FDG-PET/CTGlucose MetabolismGlycolysisImmunohistochemistryThyroid Nodule

Identifiers

PMID36253663
PMCPMC10172288
OpenAlexW4306639597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.