Evidence map›Paper›PMID 36253659›Full record

ArticleCancer causes & control : CCC2023

Smoking and pancreatic cancer: a sex-specific analysis in the Multiethnic Cohort study.

Inger T Gram, Song-Yi Park, Lynne R Wilkens, Loïc Le Marchand, Veronica Wendy Setiawan

Open access · hybridAbstract read
In one paragraph

Article in Cancer causes & control : CCC, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Do Polygenic Risk Scores Add to Clinical Data in Predicting Pancreatic Cancer? A Scoping Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Inger T GramDepartment of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Postboks 6050 Langnes, 9037, Tromsø, Norway. inger.gram@uit.no.ORCID http://orcid.org/0000-0002-0031-4152
Song-Yi ParkPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.ORCID http://orcid.org/0000-0001-7734-5320
Lynne R WilkensPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
Loïc Le MarchandPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
Veronica Wendy SetiawanDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
University of Hawaiʻi at Mānoa · USUiT The Arctic University of Norway · NOUniversity of Southern California · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Pallav Pokhrel · 1996 to 2026
$56.2M
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Investigating the cause of racial/ethnic disparity in pancreatic cancer incidenceR01CA209798 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SETIAWAN, VERONICA WENDY · 2017 to 2020
$1.8M
NCI NIH HHS N01 PC035137NCI NIH HHS N01 PC035139NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA209798NCI NIH HHS U01 CA164973NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

purposeTo examine whether the detrimental smoking-related association with pancreatic cancer (PC) is the same for women as for men.

methodsWe analyzed data from 192,035 participants aged 45-75 years, enrolled in the Multiethnic Cohort study (MEC) in 1993-1996. We identified PC cases via linkage to the Hawaii and California Surveillance, Epidemiology, and End Results Program cancer registries through December 2017.

resultsDuring a mean follow-up of 19.2 years, we identified 1,936 incident PC cases. Women smokers smoked on average less than men smokers. In multivariate Cox regression models, as compared with sex-specific never smokers, current smokers had a similar elevated risk of PC for women, hazard ratio (HR) 1.49 (95% CI 1.24, 1.79) and as for men, HR 1.48 (95% CI 1.22, 1.79) (p

conclusionAlthough MEC women smoke on average less than their men counterparts, the smoking-related increase in PC risk and the benefits of cessation seem to be of similar magnitudes for women as for men.

Indexed as

Pancreatic NeoplasmsSmoking CessationCohort StudiesFemaleHumansMaleProportional Hazards ModelsRisk FactorsSmokingCohort studiesMultiethnic Cohort (MEC) StudyPancreatic cancerSmokingSmoking cessation

Identifiers

PMID36253659
PMCPMC9816198
OpenAlexW4306655825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.