Evidence map›Paper›PMID 36253295›Full record

ArticleAnnals of emergency medicine2023

Outcomes Associated With Rural Emergency Department Provider-to-Provider Telehealth for Sepsis Care: A Multicenter Cohort Study.

Nicholas M Mohr, Uche Okoro, Karisa K Harland, Brian M Fuller, Kalyn Campbell, Morgan B Swanson, Cole Wymore, Brett Faine, Anne Zepeski, Edith A Parker and 9 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Annals of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. The impact of telehealth in sepsis care: A systematic review.Journal of telemedicine and telecare · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Effect of Sepsis Recognition on Telemedicine Use in Rural Emergency Department Sepsis Treatment.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2025
    Article
  8. Article
  9. Provider-to-provider telemedicine for sepsis is used less frequently in communities with high social vulnerability.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Nicholas M MohrDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Division of Critical Care, Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City, IA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA. Electronic address: nicholas-mohr@uiowa.edu.
Uche OkoroDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Karisa K HarlandDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Brian M FullerDivision of Critical Care, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO; Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO.
Kalyn CampbellDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Department of Surgery, Hennepin County Medical Center, Minneapolis, MN.
Morgan B SwansonDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Cole WymoreDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Brett FaineDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Department of Pharmaceutical Practice, College of Pharmacy, University of Iowa, Iowa City, IA.
Anne ZepeskiDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Edith A ParkerDepartment of Community and Behavioral Health, University of Iowa College of Public Health, Iowa City, IA.
Luke MackAvel eCare, Sioux Falls, SD; Department of Family Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, SD.
Amanda BellAvel eCare, Sioux Falls, SD.
Katie DeJongAvel eCare, Sioux Falls, SD.
Keith MuellerDepartment of Health Management and Policy, University of Iowa College of Public Health, Iowa City, IA.
Elizabeth ChrischillesDepartment of Epidemiology, University of Iowa College of Public Health, Iowa City, IA.
Christopher R CarpenterDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO.
Kelli WallaceDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.
Michael P JonesDepartment of Biostatistics, University of Iowa College of Public Health, Iowa City, IA.
Marcia M WardDepartment of Health Management and Policy, University of Iowa College of Public Health, Iowa City, IA.
University of Iowa · USWashington University in St. Louis · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
Evaluating the Role of Telemedicine in Improving Rural Emergency Department Sepsis CareK08HS025753 · AHRQ · UNIVERSITY OF IOWA · PI MOHR, NICHOLAS M. · 2019 to 2023
$717k
AHRQ HHS K08 HS025753NCATS NIH HHS UL1 TR002537NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

STUDY

objectiveTo test the hypothesis that provider-to-provider tele-emergency department care is associated with more 28-day hospital-free days and improved Surviving Sepsis Campaign (SSC) guideline adherence in rural emergency departments (EDs).

methodsMulticenter (n=23), propensity-matched, cohort study using medical records of patients with sepsis from rural hospitals in an established, on-demand, rural video tele-ED network in the upper Midwest between August 2016 and June 2019. The primary outcome was 28-day hospital-free days, with secondary outcomes of 28-day inhospital mortality and SSC guideline adherence.

resultsA total of 1,191 patients were included in the analysis, with tele-ED used for 326 (27%). Tele-ED cases were more likely to be transferred to another hospital (88% versus 8%, difference 79%, 95% confidence interval [CI] 75% to 83%). After matching and regression adjustment, tele-ED cases did not have more 28-day hospital-free days (difference 0.07 days more for tele-ED, 95% CI -0.04 to 0.17) or 28-day inhospital mortality (adjusted odds ratio [aOR] 0.51, 95% CI 0.16 to 1.60). Adherence with both the SSC 3-hour bundle (aOR 0.59, 95% CI 0.28 to 1.22) and complete bundle (aOR 0.45, 95% CI 0.02 to 11.60) were similar. An a priori-defined subgroup of patients treated by advanced practice providers suggested that the mortality was lower in the cohort with tele-ED use (aOR 0.11, 95% CI 0.02 to 0.73) despite no significant difference in complete SSC bundle adherence (aOR 2.88, 95% CI 0.52 to 15.86).

conclusionRural emergency department patients treated with provider-to-provider tele-ED care in a mature network appear to have similar clinical outcomes to those treated without.

Indexed as

Emergency Medical ServicesSepsisTelemedicineCohort StudiesEmergency Service, HospitalGuideline AdherenceHumans

Identifiers

PMID36253295
PMCPMC9780149
OpenAlexW4306319424

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.