ArticleLearning & memory (Cold Spring Harbor, N.Y.)2022
Targeted memory reactivation during sleep can induce forgetting of overlapping memories.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Concurrent Presentation of Memory-Related Odours and Sounds Nullified Sleep Reactivation Benefits.Journal of sleep research · 2026Article
- Temporal proximity to sleep determines emotional memory interference.Learning & memory (Cold Spring Harbor, N.Y.) · 2026Article
- Manipulating memory processing during sleep to explore the critical duration of reactivation events.Neuropsychologia · 2025Article
- Task-relevant representational spaces in human memory traces.PLoS computational biology · 2025Article
- Updating social evaluation during sleep.NPJ science of learning · 2025Article
- Top-down instruction outweighs emotional salience: nocturnal sleep physiology indicates selective memory consolidation.Frontiers in behavioral neuroscience · 2025Article
- Memory reactivation generates new, adaptive behaviours that reach beyond direct experience.Scientific reports · 2024Article
- Targeted memory reactivation with sleep disruption does not weaken week-old memories.NPJ science of learning · 2024Article
- Aversive memories can be weakened during human sleep via the reactivation of positive interfering memories.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Spindle-locked ripples mediate memory reactivation during human NREM sleep.Nature communications · 2024Article
- Memory Reactivation during Sleep Does Not Act Holistically on Object Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Engram mechanisms of memory linking and identity.Nature reviews. Neuroscience · 2024Review
- Delineating memory reactivation in sleep with verbal and non-verbal retrieval cues.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- When memories get complex, sleep comes to their rescue.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Memory reactivation during sleep does not act holistically on object memory.bioRxiv : the preprint server for biology · 2024Article
- Memory reactivation in slow wave sleep enhances relational learning in humans.Communications biology · 2024Article
- Sleep shapes the associative structure underlying pattern completion in multielement event memory.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Item-specific neural representations during human sleep support long-term memory.PLoS biology · 2023Article
- Review
- The effects of sleep and targeted memory reactivation on the consolidation of relevant and irrelevant information.Frontiers in sleep · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Memory reactivation during sleep can shape new memories into a long-term form. Reactivation of memories can be induced via the delivery of auditory cues during sleep. Although this targeted memory reactivation (TMR) approach can strengthen newly acquired memories, research has tended to focus on single associative memories. It is less clear how TMR affects retention for overlapping associative memories. This is critical, given that repeated retrieval of overlapping associations during wake can lead to forgetting, a phenomenon known as retrieval-induced forgetting (RIF). We asked whether a similar pattern of forgetting occurs when TMR is used to cue reactivation of overlapping pairwise associations during sleep. Participants learned overlapping pairs-learned separately, interleaved with other unrelated pairs. During sleep, we cued a subset of overlapping pairs using TMR. While TMR increased retention for the first encoded pairs, memory decreased for the second encoded pairs. This pattern of retention was only present for pairs not tested prior to sleep. The results suggest that TMR can lead to forgetting, an effect similar to RIF during wake. However, this effect did not extend to memories that had been strengthened via retrieval prior to sleep. We therefore provide evidence for a reactivation-induced forgetting effect during sleep.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.