Evidence map›Paper›PMID 36252943›Full record

ArticleOsteoarthritis and cartilage2023

Patellofemoral contact forces and knee gait mechanics 3 months after ACL reconstruction are associated with cartilage degradation 24 months after surgery.

J R Williams, K Neal, A Alfayyadh, J J Capin, A Khandha, K Manal, L Snyder-Mackler, T S Buchanan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J R WilliamsDepartment of Mechanical Engineering, University of Delaware, Newark, DE, USA. Electronic address: jackrw@udel.edu.
K NealDepartment of Mechanical Engineering, University of Delaware, Newark, DE, USA. Electronic address: kaeneal@udel.edu.
A AlfayyadhBiomechanics and Movement Science, University of Delaware, Newark, DE, USA; Physical Therapy and Rehabilitation Department, Jouf University, Jouf, Saudi Arabia. Electronic address: fayyadh@udel.edu.
J J CapinDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA. Electronic address: jacob.capin@marquette.edu.
A KhandhaDepartment of Biomedical Engineering, University of Delaware, Newark, DE, USA. Electronic address: ashutosh@udel.edu.
K ManalBiomechanics and Movement Science, University of Delaware, Newark, DE, USA; Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA. Electronic address: manal@udel.edu.
L Snyder-MacklerBiomechanics and Movement Science, University of Delaware, Newark, DE, USA; Department of Biomedical Engineering, University of Delaware, Newark, DE, USA; Department of Physical Therapy, University of Delaware, Newark, DE, USA. Electronic address: smack@udel.edu.
T S BuchananDepartment of Mechanical Engineering, University of Delaware, Newark, DE, USA; Biomechanics and Movement Science, University of Delaware, Newark, DE, USA; Department of Biomedical Engineering, University of Delaware, Newark, DE, USA. Electronic address: buchanan@udel.edu.

Funding

ACL Reconstructed Knee: qMRI and Biomechanical ModelingR01HD087459 · NICHD · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2016 to 2020
$1.8M
Contralateral Knee Osteoarthritis Among Older Adults after Primary Total Knee ArthroplastyF32AG066274 · NIA · UNIVERSITY OF COLORADO DENVER · PI CAPIN, JACOB J · 2019 to 2021
$94k
Walking Mechanics, Early Osteoarthritis Development, and Neuromuscular Training after Traumatic Knee InjuryF30HD096830 · NICHD · UNIVERSITY OF DELAWARE · PI CAPIN, JACOB J · 2018 to 2019
$53k
NIA NIH HHS F32 AG066274NICHD NIH HHS F30 HD096830NICHD NIH HHS R01 HD087459
6 · The paper itself

Abstract

objectiveEvaluate patellofemoral cartilage health, as assessed by quantitative magnetic resonance imaging (qMRI) T

designThirty individuals completed motion analysis during overground walking at a self-selected speed 3 months after ACLR. An EMG-driven neuromusculoskeletal model was used to determine muscle forces, which were then used in a previously described model to estimate patellofemoral contact forces. Biomechanical variables of interest included peak patellofemoral contact force, peak knee flexion angle and moment, and walking speed. These same participants underwent a sagittal bilateral T

resultsProlonged involved limb trochlear T

conclusionsAltered involved limb trochlear cartilage health is present 24-months after ACLR and may be related to patellofemoral loading and other walking gait mechanics 3 months after surgery.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionCartilage, ArticularOsteoarthritis, KneeBiomechanical PhenomenaGaitHumansKnee JointMagnetic Resonance ImagingACL ReconstructionBiomechanicsGaitPatellofemoralT(2) relaxation time

Identifiers

PMID36252943
PMCPMC9771964

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.