Evidence map›Paper›PMID 36252936›Full record

Trial reportContemporary clinical trials2022

Implementation of active injury management (AIM) in youth with acute concussion: A randomized controlled trial.

D G Thomas, H Erpenbach, R W Hickey, D Waltzman, J Haarbauer-Krupa, L D Nelson, C G Patterson, M A McCrea, M W Collins, A P Kontos

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Contemporary clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

D G ThomasMedical College of Wisconsin, Department of Pediatrics, United States of America. Electronic address: dthomas@mcw.edu.
H ErpenbachMedical College of Wisconsin, Department of Pediatrics, United States of America.
R W HickeyUniversity of Pittsburgh, Department of Pediatrics, United States of America.
D WaltzmanCenters for Disease Control and Prevention, United States of America.
J Haarbauer-KrupaCenters for Disease Control and Prevention, United States of America.
L D NelsonMedical College of Wisconsin, Department of Neurosurgery, United States of America.
C G PattersonUniversity of Pittsburgh, Department of Physical Therapy, United States of America.
M A McCreaMedical College of Wisconsin, Department of Neurosurgery, United States of America.
M W CollinsUniversity of Pittsburgh, Department of Orthopedic Surgery, United States of America.
A P KontosUniversity of Pittsburgh, Department of Orthopedic Surgery, United States of America.

Funding

Promoting Recovery in Children Who Sustain a Mild Traumatic Brain Injury: The TBI Evaluation and Management (TEaM) ToolkitU01CE002939 · CE · EMORY UNIVERSITY · PI SIMON, HAROLD KENNETH, WRIGHT, DAVID W · 2018 to 2021
$2.2M
ACL HHS U01CE002939NCIPC CDC HHS U01 CE002939NCIPC CDC HHS U01 CE002944
6 · The paper itself

Abstract

backgroundNearly 2 million youth seek acute medical care following concussion in the U.S. each year. Current standard of care recommends rest for the first 48 h after a concussion. However, research suggests that prolonged rest may lengthen recovery time especially for patients with certain risk profiles. Research indicates that physical activity and behavioral management interventions (sleep, stress management) may enhance recovery. To date, there is limited empirical evidence to inform acute (<72 h) concussion recommendations for physical activity and behavioral management in adolescents.

objectiveTo determine the effectiveness of physical activity and behavioral management for acute concussion in adolescents and young adults, and to evaluate the role of patient characteristics on treatment response.

methodsThis multicenter prospective randomized controlled trial will determine which combination of physical activity and behavioral management is most effective for patients 11-24 years old who present to the emergency department or concussion clinic within 72 h of injury. Participants are randomized into: 1) rest, 2) physical activity, 3) mobile health application (mHealth) behavioral management, or 4) physical activity and mHealth app conditions. Assessments at enrollment, 3-5 days, 14 days, 1 month, and 2 months include: concussion symptoms, balance, vestibular-ocular and cognitive assessments, quality of life, and recovery time. Somatic symptoms and other risk factors are evaluated at enrollment. Compliance with treatment and symptoms are assessed daily using actigraph and daily self-report. The primary study outcome is symptoms at 14 days.

conclusionPrescribed physical activity and behavioral management may improve outcomes in youth following acute concussion.

Indexed as

Brain ConcussionPost-Concussion SyndromeAdolescentAdultChildExerciseHumansProspective StudiesQuality of LifeYoung AdultClinical trialConcussionPediatrics

Identifiers

PMID36252936
PMCPMC10924688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.