Evidence map›Paper›PMID 36252817›Full record

ArticleNeurochemistry international2022

Social isolation induces succinate dehydrogenase dysfunction in anxious mice.

Saki Watanabe, Alzahra J Al Omran, Amy S Shao, Zeyu Zhang, Chen Xue, Jifeng Zhang, Junji Watanabe, Jing Liang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurochemistry international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Saki WatanabeTitus Family Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA.
Alzahra J Al OmranTitus Family Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA.
Amy S ShaoHomer Stryker M.D. School of Medicine, Western Michigan University, Kalamazoo, MI, 49007, USA.
Zeyu ZhangTranslational Research Laboratory, School of Pharmacy, University of Southern California, Los Angeles, CA, 90033, USA.
Chen XueTitus Family Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA.
Jifeng ZhangTitus Family Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA.
Junji WatanabeTranslational Research Laboratory, School of Pharmacy, University of Southern California, Los Angeles, CA, 90033, USA.
Jing LiangTitus Family Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA. Electronic address: jliang1@usc.edu.
University of Southern California · USStryker (United States) · US

Funding

Mechanisms underlying effects of Hovenia-dihydromyricetin on alcohol intoxicationR21AA017991 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIANG, JING · 2009 to 2010
$415k
NIAAA NIH HHS R21 AA017991
6 · The paper itself

Abstract

We have previously reported social isolation induces anxiety-like behavior, cognitive decline, and reduction in brain ATP levels in mice. These changes were ameliorated by treatment with dihydromyricetin (DHM), a compound that positively modulates γ-aminobutyric A (GAB

Indexed as

Cognitive DysfunctionSuccinate DehydrogenaseAdenosine TriphosphateAnimalsAnxietyMiceSocial IsolationAdenosine TriphosphateSuccinate DehydrogenaseAnxietyComplex IIDihydromyricetinSocial isolationStressSuccinate dehydrogenase

Identifiers

PMID36252817
PMCPMC9719728
OpenAlexW4306181789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.