Evidence map›Paper›PMID 36252719›Full record

ArticleMolecular and cellular neurosciences2022

Axonal transport deficits in neuropsychiatric disorders.

Kerriann K Badal, Sathyanarayanan V Puthanveettil

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kerriann K BadalDepartment of Neuroscience, UF Scripps Biomedical Research, University of Florida, 130 Scripps Way, Jupiter, FL 33458, USA; Integrative Biology PhD Program, Charles E. Schmidt College of Science, Florida Atlantic University, Jupiter, FL 33458, USA.
Sathyanarayanan V PuthanveettilDepartment of Neuroscience, UF Scripps Biomedical Research, University of Florida, 130 Scripps Way, Jupiter, FL 33458, USA. Electronic address: sputhanveettil@ufl.edu.
Florida Atlantic University · USScripps Research Institute · US

Funding

Transcriptomic Mechanisms of Formation and Persistence of Synapse Specific Long-Term MemoryR01MH119541 · NIMH · UNIVERSITY OF FLORIDA · PI PUTHANVEETTIL, SATHYA · 2019 to 2023
$2.7M
Axonal Transport and Long-Term Memory StorageR01MH094607 · NIMH · SCRIPPS FLORIDA · PI PUTHANVEETTIL, SATHYA · 2014 to 2018
$2.3M
The role of bidirectional transport of lysosome-related organelles in learning and memorystorageF31MH127958 · NIMH · UNIVERSITY OF FLORIDA · PI BADAL, KERRIANN · 2021 to 2023
$105k
NIMH NIH HHS F31 MH127958NIMH NIH HHS R01 MH094607NIMH NIH HHS R01 MH119541
6 · The paper itself

Abstract

Axonal transport is a major cellular process that mediates bidirectional signaling between the soma and synapse, enabling both intracellular and intercellular communications. Cellular materials, such as proteins, RNAs, and organelles, are transported by molecular motor proteins along cytoskeletal highways in a highly regulated manner. Several studies have demonstrated that axonal transport is central to normal neuronal function, plasticity, and memory storage. Importantly, disruptions in axonal transport result in neuronal dysfunction and are associated with several neurodegenerative disorders. However, we do not know much about axonal transport deficits in neuropsychiatric disorders. Here, we briefly discuss our current understanding of the role of axonal transport in schizophrenia, bipolar and autism.

Indexed as

Axonal TransportSynapsesAxonsNeuronsSignal TransductionAxonal transportMitochondriaMolecular motorsNeuropsychiatric disordersSynaptic connectivitySynaptic plasticity

Identifiers

PMID36252719
PMCPMC12717855
OpenAlexW4306194631

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.